Migraine in Adolescents

Inclusion criteria for healthy participants:

1. Age 10-13
2. Males or females (biological sex)
3. Not diagnosed with migraine or having migraine symptoms
4. With a first degree relative diagnosed with migraine (for the Fam-His group) or without a first or a second degree relative diagnosed with migraine (for the No-Fam-His group)

Inclusion criteria for participants with migraine:

1. Age 10-13
2. Males or females (biological sex)
3. Diagnosed with migraine or having migraine symptoms
4. Migraine duration \> 6 months
5. Without preventative treatment or with stable preventative treatment for migraine (no change in intervention in the last 6 months)

Exclusion Criteria for the healthy group:

* Participants will not be enrolled if any of the following criteria exist and based on the investigator discretion:

  1. Diagnosis of any chronic pain syndrome
  2. Diagnosis of a neurological, developmental, pubertal, or psychiatric disorder
  3. Taking pain or psychiatric medications regularly
  4. Having an MRI contraindication such as metal in the body or claustrophobia
  5. Not able to understand and communicate in English

     Exclusion Criteria for the migraine group
* Participants will not be enrolled if any of the following criteria exist and based on the investigator discretion:

  1. Diagnosis of any chronic pain syndrome other than migraine
  2. Diagnosis of a neurological, developmental, pubertal, or psychiatric disorder
  3. Having an MRI contraindication such as metal in the body or claustrophobia
  4. Not able to understand and communicate in English