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Application of a Clinical Decision Support System to Reduce Mechanical Ventilation Duration After Cardiac Surgery in Children

Application of a Clinical Decision Support System to Reduce Mechanical Ventilation Duration After Cardiac Surgery

Who can join

1 Day – 12 Years · All sexes

Inclusion Criteria:

* Children \< 12 years old
* Post-cardiac surgery
* Receiving mechanical ventilation for ≥ 48 hours in the Cardiac Intensive Care Unit at Boston Children's Hospital following surgery

Exclusion Criteria:

* Premature infants (\<37 weeks' gestation)
* Weight \< 2kg
* Baseline ventilator (via tracheostomy) or noninvasive positive pressure dependence

About the study

The goal of this study is to evaluate the impact of a clinical decision support system (CDSS) in children receiving mechanical ventilation (MV) after surgery for congenital heart disease (CHD). The main question it aims to answer is:

-What is the impact of a CDSS designed to facilitate weaning and discontinuation of MV on the duration of MV in post-operative congenital cardiac surgery patients?

Participants will be identified as eligible to initiate weaning from mechanical ventilation. Providers will decide whether or not to initiate weaning based on recommendations provided by the CDSS. Researchers will compare patients exposed to the CDSS with a historical cohort to see if the CDSS facilitated a decrease in MV duration.

What is being tested

• Clinical decision support system (CDSS) for ventilator weaning (device)

Sponsor: Boston Children's Hospital · Participants: 330 · Started: Nov 18, 2024

Contact the study team

• Daniel L Hames, MD · Phone: 6173554023

Official record on ClinicalTrials.gov — NCT05687292

Locations in the U.S.

Conditions

• Congenital Heart Defects

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.