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Towards a Wearable Alcohol Biosensor: Examining the Accuracy of BAC Estimates From New-Generation Transdermal Technology Using Large-Scale Human Testing and Machine Learning Algorithms

RecruitingObservational studyHealthy volunteers welcome

Who can join

Ages 21 and older · All sexes · Healthy volunteers welcome

Full eligibility criteria
Inclusion Criteria:

* 21 years or older
* drink alcohol at least 2x weekly

Exclusion Criteria:

* psychological or medical conditions that might contraindicate alcohol-administration
* history of adverse reaction to type and amount of beverage used in the study
* currently seeking treatment for alcohol use disorder
* does not drink alcohol regularly
* taking drugs or medications for which alcohol consumption would be contraindicated
* women who are pregnant or are attempting to become pregnant

About the study

The study will employ a combined laboratory-ambulatory design. Participants will engage in ambulatory assessment over the course of 14 days, wearing biosensors assessing transdermal alcohol concentration (TAC) and providing breathalyzer readings in real-world contexts. Also during this period, participants will attend three laboratory alcohol-administration sessions scheduled at one-week intervals, with alcohol dose and rate of consumption manipulated within and between participants, respectively. Laboratory visits will also double as ambulatory orientation, check-in, and close-out sessions.

What is being tested

Sponsor: University of Illinois at Urbana-Champaign · Participants: 240 · Started: Oct 22, 2022

Contact the study team

Official record on ClinicalTrials.gov — NCT05692830

Locations in the U.S.

IllinoisUniversity of Illinois at Urbana-Champaign, Champaign

Conditions

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.