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Alcohol clinical trials recruiting in the U.S.
76 studies for Alcohol are recruiting participants at sites across the United States.
Many people drink alcohol. Drinking too much can take a serious toll on your health. It's important to know how alcohol affects you and how much is too much.
Cities with the most studies
- New Haven, CT7 studies
- Boston, MA5 studies
- Washington, DC4 studies
- Providence, RI4 studies
- New York City, NY3 studies
- Baltimore, MD3 studies
- Philadelphia, PA3 studies
- Charleston, SC3 studies
- Seattle, WA3 studies
- Champaign, IL3 studies
By state
- California5 studies
- Connecticut7 studies
- Florida4 studies
- Illinois4 studies
- Maryland6 studies
- Massachusetts5 studies
- New York5 studies
- Pennsylvania5 studies
- Rhode Island4 studies
- South Carolina3 studies
- Texas11 studies
- Washington4 studies
Recently updated studies
Letter-Writing Add-On to Brief Motivational Intervention for Alcohol Use
Recruiting
Ages 18 and older · All sexes · Updated Nov 13, 2026 · NCT07926880Nicotinic Receptor Genetic Variation and Alcohol Reward
RecruitingPhase 1Healthy volunteers welcome
Ages 21 to 60 · All sexes · Updated Nov 12, 2026 · NCT03294460Evaluating Caregiver Involvement in Primary Care-Based Brief Interventions for Adolescent Alcohol Use Problems
Recruiting
Ages 12 to 18 · All sexes · Updated Nov 9, 2026 · NCT06593652Spironolactone in Alcohol Use Disorder (SAUD)
RecruitingPhase 1
Ages 21 to 99 · All sexes · Updated Nov 9, 2026 · NCT05807139Semaglutide Dose Effects on Metabolic and Stress Hormone, Craving and Alcohol Use Outcomes
RecruitingPhase 1
Ages 18 to 68 · All sexes · Updated Nov 4, 2026 · NCT07772960Precision Microbiota Interventions for Senoreduction Trial
RecruitingPhase 1/2
Ages 40 and older · All sexes · Updated Oct 29, 2026 · NCT07462767Adjunctive Motivational Alcohol Intervention to Prevent IPV
Recruiting
Ages 18 and older · All sexes · Updated Oct 23, 2026 · NCT05287711MATAspire: Mental Health Awareness Tailored App for Substance Prevention and Integrated Resilience Education
RecruitingHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Oct 22, 2026 · NCT06553196ChangeGradients: Promoting Adolescent Health Behavior Change
RecruitingHealthy volunteers welcome
Ages 15 to 17 · All sexes · Updated Oct 22, 2026 · NCT04110756Acceptance and Commitment Therapy for HIV+ Hazardous Drinkers
Recruiting
Ages 18 and older · All sexes · Updated Oct 20, 2026 · NCT06648629A SMART Evaluation of an Adaptive Web-based AUD Treatment for Service Members and Their Partners
RecruitingHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Oct 19, 2026 · NCT05619185Maternal Outcomes: Mood, Alcohol Use, and Depressive Symptoms
Recruiting
Ages 18 and older · Women · Updated Oct 13, 2026 · NCT07485036Reducing Cardiovascular Risks: The Role of Alcohol Use
Recruiting
Ages 26 to 49 · All sexes · Updated Oct 6, 2026 · NCT07783061Cannabis' Impact on Alcohol Consumption
RecruitingPhase 2Healthy volunteers welcome
Ages 21 to 50 · All sexes · Updated Oct 5, 2026 · NCT05389930HIV and Alcohol Research Center Focused on Polypharmacy (HARP) Pilot 2 (2nd HARP Pilot Intervention)
RecruitingPhase 1
Ages 50 and older · All sexes · Updated Sep 25, 2026 · NCT06513819Effect of Sublingual Formulation of Dexmedetomidine Hydrochloride (HCl) (BXCL501) - Outpatient Study
RecruitingPhase 1
Ages 21 to 65 · All sexes · Updated Sep 21, 2026 · NCT06335407Exercise Training Decreases Alcohol Consumption and Tissue Injury by an FGF21-dependent Mechanism
Recruiting
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT07824089Brief Motivational Interviewing +/- Mindfulness Training for Adolescent Alcohol Use in Pediatric Primary Care
Recruiting
Ages 12 to 17 · All sexes · Updated Sep 11, 2026 · NCT07059078The Potential Therapeutic Effects of Psychedelic, N, N-dimethyltryptamine (DMT), on Alcohol Use Disorder (AUD)
RecruitingPhase 1
Ages 21 to 65 · All sexes · Updated Sep 10, 2026 · NCT06070649Alcohol, Breast Cancer, and Metabolism
RecruitingHealthy volunteers welcome
Ages 21 to 45 · Women · Updated Sep 8, 2026 · NCT07779967Role of Phosphatidylethanol in Predicting Perioperative Outcomes of Admitted Patients at UHCMC
RecruitingObservational study
Ages 21 to 79 · All sexes · Updated Sep 4, 2026 · NCT06864819Microbiome Metabolites and Alcohol in HIV to Reduce CVD RCT
RecruitingPhase 2
Ages 18 to 89 · All sexes · Updated Aug 27, 2026 · NCT05288790Partnering to Enhance Emerging Adults' Response to Programs
RecruitingHealthy volunteers welcome
Ages 18 to 24 · All sexes · Updated Aug 25, 2026 · NCT06115252Influence of Mavoglurant on Alcohol Craving and Drinking in Heavy Drinkers
RecruitingPhase 1
Ages 21 to 50 · All sexes · Updated Aug 21, 2026 · NCT06136195Smartphone-based Intervention for Young Adults With ADHD
Recruiting
Ages 18 to 25 · All sexes · Updated Aug 18, 2026 · NCT07654205From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.