Oklahoma Study of Native American Pain Risk III: Stress and Resilience
The Impact of Structural Racism and Discrimination (SRD) on Mechanisms of the Native American Pain Disparity
Who can join
Ages 18 and older · All sexes · Healthy volunteers welcome
Full eligibility criteria
Inclusion Criteria: * Self-identify as Native American/American Indian Exclusion Criteria: * \<18 years of age * Self-reported history of cardiovascular, neuroendocrine, musculoskeletal, or neurological disorders * Surrent chronic pain, defined as persistent, bothersome pain on more days than not for at least 3 months) * Self-reported current substance dependence * Sse of medication that could interfere with testing (e.g., recent use of analgesics, antidepressants, or anti-anxiety medications) * Inability to speak English * Current psychosis (assessed by Psychosis Screening Questionnaire) * Serious cognitive impairment (assessed by \<20 score on the Montreal Cognitive Assessment \[MoCA\]) * Possible peripheral neuropathy (assessed by nerve conduction study)
About the study
The goal of this observational study is to learn about the relationship between environmental structural racism and discrimination and chronic pain risk in Native American adults. The main questions it aims to answer are:
1. How does environmental structural racism and discrimination affect chronic pain-promoting mechanisms in Native Americans? 2. What psychosocial factors buffer the negative effects of environmental structural racism and discrimination on chronic pain-promoting mechanisms?
Sponsor: University of Oklahoma · Participants: 220 · Started: Feb 3, 2023
Contact the study team
- PLAN Lab · Phone: 918-660-3048
- Jamie L Rhudy, PhD · Phone: 918-660-3050
Official record on ClinicalTrials.gov — NCT05723081
Locations in the U.S.
| Oklahoma | University of Oklahoma - Schusterman Center, Tulsa |
Conditions
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.