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Effects of RAS on Gait in PD Patients With DBS
Effects of Rhythmic Auditory Stimulation (RAS) on Gait in Parkinson Disease (PD) Patients With DBS
Who can join
Ages 18 to 89 · All sexes
Full eligibility criteria
Inclusion Criteria: * Patients diagnosed with Parkinson disease (PD) (and) * PD patients who implanted Deep Brain Stimulation (DBS) of the subthalamic nucleus (STN) with PerceptTM PC Exclusion Criteria: * Inability or unwillingness to follow directions for study procedures
About the study
Participants will be asked to walk along with the metronome beats (RAS) during the participants' stimulation state (ON or OFF) for four minutes for each state.
The researcher will collect the gait parameters (cadence, velocity, and stride length) of patients before, during, and after RAS in both DBS ON and OFF states.
Using MDS-UPDRS, participants' gait patterns will be collected before and after RAS while both DBS is ON and OFF. Electrophysiological activity (local field potentials, LFPs) will be collected across all stages (pre, during, and post-RAS) of evaluation.
What is being tested
- Rhythmic Auditory Stimulation (RAS) (behavioral)
Sponsor: Johns Hopkins University · Participants: 10 · Started: Aug 1, 2023
Contact the study team
- Alexander Pantelyat, MD · Phone: 4105023290
Official record on ClinicalTrials.gov — NCT05763732
Locations in the U.S.
| Maryland | Johns Hopkins School of Medicine, Baltimore |
Conditions
From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.