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Long-Term Safety of Lutetium (177Lu) Vipivotide Tetraxetan in Participants With Prostate Cancer

RecruitingPhase 4

A Phase IV, Post-Authorization Safety Study to Investigate the Long-Term Safety of Lutetium (177Lu) Vipivotide Tetraxetan in Adult Participants With Prostate Cancer

Who can join

Ages 18 to 100 · Men

Full eligibility criteria
Inclusion Criteria:

* Signed informed consent must be obtained prior to participation in the study
* Must have received at least one dose of AAA617 within an interventional, Phase I-IV Novartis sponsored clinical trial in prostate cancer and have fulfilled the trial's requirements that allows them to participate in this study.

Exclusion Criteria:

\- Inability to complete the needed investigational examinations due to any reason.

About the study

The purpose of this post-marketing study is to further characterize the long-term outcome of known or potential risks of lutetium (177Lu) vipivotide tetraxetan also known as \[177Lu\]Lu-PSMA-617 or 177Lu-PSMA-617 and hereinafter referred to as AAA617. The study also seeks to further characterize (as possible) any other AAA617 causally related serious adverse event(s) in the long-term in adults with prostate cancer who received at least one dose of AAA617 from interventional, Phase I-IV Novartis sponsored clinical trials.

What is being tested

Sponsor: Novartis Pharmaceuticals · Participants: 700 · Started: Aug 14, 2023

Contact the study team

Official record on ClinicalTrials.gov — NCT05803941

Locations in the U.S.

ArizonaMayo Clinic Arizona, Scottsdale
CaliforniaSt. Joseph Hospital, Orange
Providence Saint Johns Health Ctr, Santa Monica
ColoradoUniversity of Colorado, Aurora
ConnecticutHartford Hospital, Hartford
District of ColumbiaVA Medical Center, Washington D.C.
FloridaMayo Clinic Jacksonville, Jacksonville
GeorgiaUniversity Cancer and Blood Center LLC, Athens
IndianaParkview Research Center, Fort Wayne
LouisianaOchsner Clinic Foundation, New Orleans
Tulane Cancer Center, New Orleans
MichiganCorewell Health William Beaum Hosp, Royal Oak
MinnesotaMayo Clinic Rochester, Rochester
MississippiUniversity of Mississippi Med Ctr, Jackson
MissouriWash U School of Medicine, St Louis
NebraskaNebraska Cancer Specialists, Omaha
Urology Cancer Center PC, Omaha
New YorkMontefiore Medical Center, The Bronx
North CarolinaDuke University Medical Center, Durham
OhioCleveland Clinic Foundation, Cleveland
PennsylvaniaUniv of Pittsburgh Medical Center, Pittsburgh
TexasUniv of Texas Southwest Med Center, Dallas
UT Health Science Center, Houston
VirginiaOnco Hemato Asso of SW Virginia, Roanoke

Conditions

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.