Transcranial Direct Current Stimulation for Post-stroke Fatigue
RecruitingPhase 2
Home-based Post-stroke Fatigue Treatment Using Transcranial Direct Current Stimulation (tDCS)
Who can join
Ages 18 and older · All sexes
Full eligibility criteria
Inclusion Criteria: * Male or female patients aged \>18 years * Greater than 3 months from first hemorrhagic or ischemic stroke (subacute to chronic), confirmed through neuroimaging (CT or MRI). * Fatigue severity score average \>4 (severe fatigue) * Willingness to remain stable on pharmacologic therapy through the duration of the study. * Availability of a caregiver, family member, or friend to be present during the administration of the tDCS intervention. Exclusion Criteria: * Metal in the head (except mouth) or implanted cranial or thoracic devices (i.e. pacemaker, DBS stimulator) * History of seizure * History of moderate to severe traumatic brain injury * A score of 10 or more on the PHQ-9 or GAD-7 scale, suggestive of moderate to severe depression/anxiety. * A score of less than 21 on the MoCA suggesting major neurocognitive disorder. * Signs of skin rash, infection, or laceration in the supraorbital region where the tDCS will be applied. * Inability to provide informed consent * Other major neurological, medical, or psychiatric illnesses that could confound results in the opinion of the site investigator.
About the study
The investigators hypothesize that delivery of anodal tDCS to the left frontal head region will reduce fatigue severity following stroke.
What is being tested
- Real Soterix Mini-CT tDCS stimulator (device)
- Sham Soterix Mini-CT tDCS stimulator (device)
Sponsor: Weill Medical College of Cornell University · Participants: 24 · Started: May 23, 2023
Contact the study team
- Zhiyan Yang, M.A. · Phone: (212) 746-1509
Official record on ClinicalTrials.gov — NCT05816603
Locations in the U.S.
| New York | Weill Cornell Medicine, 525 E. 68th St, Baker Pavilion, F-2106, New York |
Conditions
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.