Home › Quitting Smoking › NCT05846841
Personalized Tobacco Treatment in Primary Care (MOTIVATE)
A Multilevel Intervention to Personalize and Improve Tobacco Treatment in Primary Care (MOTIVATE)
Who can join
Ages 18 and older · All sexes
Full eligibility criteria
Eligibility Criteria for Primary and Specialty Care Clinicians * Clinician from participating clinic * At least 18 years of age * Can speak and understand English Eligibility Criteria for Primary Care and Specialty Patients Inclusion: * Patient at participating clinic * Age 18 years or older, inclusive * Current smoking (cigarettes per day \>=5) * Can speak and understand English * Willing to consider medication to help reduce craving or smoking such as nicotine patch, lozenge, or varenicline Exclusion: * Active use of smoking cessation medication (within the past 30 days) * Receipt of smoking cessation medication or prescription for smoking cessation medication (within the past 30 days) * Having a contraindication for cNRT or varenicline (allergic reactions, current cardiac problems, pregnancy)
About the study
This study examines the application of precision treatment intervention for smoking cessation from both the clinician perspective and patient perspective, and compares it to usual care on tobacco treatment in the primary care setting. The precision treatment intervention includes personalized tobacco treatment recommendations using the patient's clinical, genetic, and biomarker information. This approach may increase effectiveness and adherence for the patient, and increase the clinician's likelihood of prescribing.
What is being tested
- Precision Treatment (behavioral)
- Usual Care (behavioral)
Sponsor: Washington University School of Medicine · Participants: 850 · Started: Sep 29, 2023
Contact the study team
- Li-Shiun Chen, ScD, MD, MPH · Phone: 314-362-3932
- Alex Ramsey, PhD · Phone: 314-362-5370
Official record on ClinicalTrials.gov — NCT05846841
Locations in the U.S.
| Missouri | Washington University School of Medicine, St Louis |
Conditions
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.