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Quitting Smoking clinical trials recruiting in the U.S.
74 studies for Quitting Smoking are recruiting participants at sites across the United States.
Quitting smoking is important for your health. Tobacco use is the most common preventable cause of death. Find the best way for you to quit.
Cities with the most studies
- Minneapolis, MN6 studies
- Chicago, IL5 studies
- Charleston, SC5 studies
- San Francisco, CA5 studies
- Oklahoma City, OK4 studies
- Boston, MA3 studies
- Houston, TX3 studies
- New York City, NY3 studies
By state
- California9 studies
- Colorado3 studies
- Florida3 studies
- Illinois6 studies
- Kansas3 studies
- Massachusetts4 studies
- Minnesota7 studies
- Missouri4 studies
- New Jersey3 studies
- New York5 studies
- North Carolina3 studies
- Oklahoma6 studies
- South Carolina5 studies
- Texas6 studies
- Virginia3 studies
- Wisconsin3 studies
Recently updated studies
Pain and Smoking Study 2.0: A Randomized Clinical Trial of Smoking Cessation Among Veterans With Chronic Pain
Recruiting
Ages 18 and older · All sexes · Updated Sep 29, 2026 · NCT06442514A Study Of Vagal Nerve Stimulation In Conjunction With NRT For Smoking Cessation
RecruitingPhase 2/3
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07487818Actívatexto: Advancing Smoking Cessation and Physical Activity Among Latinos
Recruiting
Ages 18 and older · All sexes · Updated Sep 18, 2026 · NCT06926608Circuitry-Guided Smoking Cessation in Schizophrenia (UH3)
Recruiting
Ages 22 to 65 · All sexes · Updated Sep 16, 2026 · NCT05276050Varenicline and Accelerated Transcranial Magnetic Stimulation (TMS) for Quitting Nicotine Use (Pilot Study)
RecruitingPhase 4
Ages 18 to 65 · All sexes · Updated Sep 15, 2026 · NCT07145866Modulating Neural Mechanisms of Reward Processing in Tobacco Users
Recruiting
Ages 18 to 60 · All sexes · Updated Sep 10, 2026 · NCT07812753Trauma-Informed Care for Smoking Cessation for Pregnancy
RecruitingHealthy volunteers welcome
Ages 18 and older · Women · Updated Sep 10, 2026 · NCT07129590Overcoming Nicotine Dependence to Enable Quitting
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 9, 2026 · NCT05513872Studying NMDA and Sigma-1 in Smoking Cessation Treatment (SUMMIT)
RecruitingPhase 3
Ages 18 to 65 · All sexes · Updated Sep 8, 2026 · NCT07766655Vaped Phenanthrene
RecruitingHealthy volunteers welcome
Ages 21 and older · All sexes · Updated Sep 3, 2026 · NCT07134426A Study Evaluating the Use of an Indoor Air Quality Monitor to Promote a Smoke-free Home
RecruitingHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Aug 27, 2026 · NCT06693700Evaluation of Low and High Nicotine Tobacco Free Nicotine Pouches
RecruitingHealthy volunteers welcome
Ages 21 and older · All sexes · Updated Aug 20, 2026 · NCT06678789Trial of Varenicline With Nicotine Lozenges and a Smartphone Medication Adherence Intervention for Smoking Cessation
RecruitingPhase 2Healthy volunteers welcomeMentions payment for participants
Ages 18 and older · All sexes · Updated Aug 19, 2026 · NCT07099638Evaluating the Impact of CONNECT in a Multilingual Population
RecruitingHealthy volunteers welcome
Ages 50 to 80 · All sexes · Updated Aug 13, 2026 · NCT07111936Family-Based Financial Incentives Intervention for Smoking Cessation
Recruiting
Ages 18 and older · All sexes · Updated Aug 10, 2026 · NCT06556433Refer2Quit: Evaluating a Proactive, Tailored, Population Health Approach for Tobacco Treatment for Household Smokers Through a Pediatric Care Network
Recruiting
Ages 18 and older · All sexes · Updated Aug 6, 2026 · NCT06582693Personalized Brain Stimulation to Help Veterans Quit Smoking
Recruiting
Ages 18 to 70 · All sexes · Updated Aug 4, 2026 · NCT07050862Personalized Tobacco Treatment in Primary Care (MOTIVATE)
Recruiting
Ages 18 and older · All sexes · Updated Aug 3, 2026 · NCT05846841Project Q: Cue-based Treatment Intervention to Promote Cessation Among People Who Smoke Lightly or Non-daily
Recruiting
Ages 18 and older · All sexes · Updated Jul 28, 2026 · NCT07425119Rural Smoking Cessation
RecruitingHealthy volunteers welcome
Ages 21 and older · All sexes · Updated Jul 27, 2026 · NCT06584929Precision Treatment to Promote Smoking Cessation and Survival in Oncology Patients
Recruiting
Ages 18 to 89 · All sexes · Updated Jul 24, 2026 · NCT07166120My Path to Quit Tobacco
RecruitingPhase 4Healthy volunteers welcome
Ages 21 and older · All sexes · Updated Jul 23, 2026 · NCT07419425Multi-Site Trial of Tirzepatide for Smoking Cessation
RecruitingPhase 2
Ages 21 to 65 · All sexes · Updated Jul 17, 2026 · NCT07602699Enhancing Smoking Cessation for African American People Everywhere
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Jul 13, 2026 · NCT07024992Modifying Progesterone and Estradiol Levels to Prevent Postpartum Cigarette Smoking Relapse and Reduce Secondhand Smoke Exposure in Infants and Children
RecruitingPhase 4
Ages 18 to 45 · Women · Updated Jul 13, 2026 · NCT04783857From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.