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Quitting Smoking clinical trials recruiting in the U.S.
75 studies for Quitting Smoking are recruiting participants at sites across the United States.
Quitting smoking is important for your health. Tobacco use is the most common preventable cause of death. Find the best way for you to quit.
Cities with the most studies
- Minneapolis, MN7 studies
- Chicago, IL5 studies
- Charleston, SC5 studies
- Boston, MA4 studies
- Oklahoma City, OK4 studies
- San Francisco, CA4 studies
- Phoenix, AZ3 studies
- New York City, NY3 studies
- Houston, TX3 studies
By state
- Arizona3 studies
- California8 studies
- Colorado3 studies
- Florida3 studies
- Illinois6 studies
- Kansas3 studies
- Massachusetts5 studies
- Minnesota8 studies
- Missouri4 studies
- New Jersey3 studies
- New York5 studies
- North Carolina5 studies
- Oklahoma6 studies
- Pennsylvania3 studies
- South Carolina6 studies
- Texas6 studies
- Virginia3 studies
- Wisconsin3 studies
Recently updated studies
Rural Smoking Cessation
RecruitingHealthy volunteers welcome
Ages 21 and older · All sexes · Updated Nov 13, 2026 · NCT06584929Using Multiphase Optimization Strategy (MOST) to Optimize a Cost-effective, Sustainable and Scalable Smoking Cessation Package for Smokers in HIV Clinical Care
RecruitingPhase 4
Ages 18 and older · All sexes · Updated Nov 12, 2026 · NCT06598397My Path to Quit Tobacco
RecruitingPhase 4Healthy volunteers welcome
Ages 21 and older · All sexes · Updated Nov 10, 2026 · NCT07419425Trial of Varenicline With Nicotine Lozenges and a Smartphone Medication Adherence Intervention for Smoking Cessation
RecruitingPhase 2Healthy volunteers welcomeMentions payment for participants
Ages 18 and older · All sexes · Updated Nov 9, 2026 · NCT07099638Optimizing Medications and Lung Health in People With HIV Through Pharmacist-led Proactive E-Consults
Recruiting
Ages 18 and older · All sexes · Updated Nov 9, 2026 · NCT07507435Studying NMDA and Sigma-1 in Smoking Cessation Treatment (SUMMIT)
RecruitingPhase 3
Ages 18 to 65 · All sexes · Updated Nov 6, 2026 · NCT07766655Scalable TELeheaLth Cancer CARe: The STELLAR Program to Treat Cancer Risk Behaviors
Recruiting
Ages 18 and older · All sexes · Updated Nov 6, 2026 · NCT05687604Personalized Tobacco Treatment in Primary Care (MOTIVATE)
Recruiting
Ages 18 and older · All sexes · Updated Nov 3, 2026 · NCT05846841Precision Treatment to Promote Smoking Cessation and Survival in Oncology Patients
Recruiting
Ages 18 to 89 · All sexes · Updated Oct 23, 2026 · NCT07166120Collection of Airway, Blood and/or Urine Specimens From Subjects for Research Studies
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Oct 23, 2026 · NCT01776398Project Q: Cue-based Treatment Intervention to Promote Cessation Among People Who Smoke Lightly or Non-daily
Recruiting
Ages 18 and older · All sexes · Updated Oct 21, 2026 · NCT07425119Testing the mHealth App Intervention for Nondaily Smokers "SiS4"
Recruiting
Ages 18 and older · All sexes · Updated Oct 13, 2026 · NCT06678243Adapting and Pilot Testing a Skills-based Smoking Cessation Intervention to Address Developmental and Health-related Stress Among Adults Who Smoke
Recruiting
Ages 18 and older · All sexes · Updated Oct 8, 2026 · NCT06654414The Avenues Study: Dual Use Cessation
RecruitingPhase 4
Ages 21 and older · All sexes · Updated Oct 7, 2026 · NCT06474299Smoking Cessation Pharmacotherapy-Nurse Practitioner Led Tobacco Treatment Team Study
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT05733767Quitting Matters Human Immunodeficiency Virus Hybrid Trial
Recruiting
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT06883097Pain and Smoking Study 2.0: A Randomized Clinical Trial of Smoking Cessation Among Veterans With Chronic Pain
Recruiting
Ages 18 and older · All sexes · Updated Sep 29, 2026 · NCT06442514A Study Of Vagal Nerve Stimulation In Conjunction With NRT For Smoking Cessation
RecruitingPhase 2/3
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07487818Actívatexto: Advancing Smoking Cessation and Physical Activity Among Latinos
Recruiting
Ages 18 and older · All sexes · Updated Sep 18, 2026 · NCT06926608Circuitry-Guided Smoking Cessation in Schizophrenia (UH3)
Recruiting
Ages 22 to 65 · All sexes · Updated Sep 16, 2026 · NCT05276050Varenicline and Accelerated Transcranial Magnetic Stimulation (TMS) for Quitting Nicotine Use (Pilot Study)
RecruitingPhase 4
Ages 18 to 65 · All sexes · Updated Sep 15, 2026 · NCT07145866Modulating Neural Mechanisms of Reward Processing in Tobacco Users
Recruiting
Ages 18 to 60 · All sexes · Updated Sep 10, 2026 · NCT07812753Trauma-Informed Care for Smoking Cessation for Pregnancy
RecruitingHealthy volunteers welcome
Ages 18 and older · Women · Updated Sep 10, 2026 · NCT07129590Overcoming Nicotine Dependence to Enable Quitting
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 9, 2026 · NCT05513872Vaped Phenanthrene
RecruitingHealthy volunteers welcome
Ages 21 and older · All sexes · Updated Sep 3, 2026 · NCT07134426From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.