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Minimally Invasive Esophagectomy Pain Control Trial
A Randomized Controlled Trial Comparing Local Intercostal Nerve Blocks, Cryo-ablation Plus Intercostal Nerve Blocks, and Serratus Plane Catheter Plus Intercostal Nerve Blocks After Minimally Invasive Esophagectomy
Who can join
Ages 18 and older · All sexes
Full eligibility criteria
Inclusion Criteria: All adult individuals who undergo an esophagectomy with an intended minimally invasive approach of the chest at Swedish Medical Center-First Hill. These approaches include: * 3-hole with R video-assisted thoracoscopic surgery (VATS) * Ivor Lewis R VATS Exclusion Criteria: * Age \<18 * Unable to consent * Additional surgical procedures planned * Patients with previous thoracic surgery * Patient with chronic pain on a daily regimen of narcotics * Non-English speaking * Contraindications to neuraxial anesthesia (ongoing anticoagulation, anticipated post-operative therapeutic anticoagulation, spinal cord stimulators, anatomic abnormalities preventing epidural placement)
About the study
A pilot randomized controlled trial comparing intercostal nerve blocks, cryo-ablation plus intercostal nerve blocks, and serratus plane catheter plus intercostal nerve blocks in patients undergoing esophagectomies with minimally invasive thoracic approaches.
What is being tested
- Local intercostal nerve block (procedure)
- Cryo-analgesia and intercostal nerve block (procedure)
- Serratus plane catheter blocks and intercostal nerve blocks (procedure)
- Thoracic epidural catheter (procedure)
Sponsor: Swedish Medical Center · Participants: 30 · Started: Apr 26, 2022
Contact the study team
- Brian Louie, M.D. · Phone: (206) 215-6800
- Meagan Ivy, M.D. · Phone: (206) 215-6800
Official record on ClinicalTrials.gov — NCT05906134
Locations in the U.S.
| Washington | Swedish Cancer Institute, Seattle |
Conditions
From ClinicalTrials.gov, data retrieved Oct 2, 2026. Each study sets its own eligibility; the study team decides who can join.