Home › Rectal Cancer › NCT05914766

An Informational and Supportive Care Intervention for Patients With Locally Advanced Rectal Cancer

PATHWAYS: An Informational and Supportive Care Intervention for Patients With Locally Advanced Rectal Cancer

Who can join

Ages 18 and older · All sexes

Inclusion Criteria:

1. Age≥18 years
2. Within 8 weeks after documented decision to pursue multi-modality therapy for newly diagnosed LARC (i.e., stage II or III disease)
3. Able to complete study procedures English or with the assistance of an interpreter

Exclusion Criteria:

1. Comorbid health condition that would interfere with study participation, as identified by cancer care team
2. Has undergone treatment for a prior colorectal cancer

About the study

The aim of this study is to evaluate the feasibility and acceptability of conducting a randomized trial of a brief psychoeducational intervention versus enhanced usual care for patients with locally advanced rectal cancer who are initiating neoadjuvant multimodality treatment.

What is being tested

• PATHWAYS (behavioral)
• Enhanced usual care (other)

Sponsor: Massachusetts General Hospital · Participants: 80 · Started: Sep 21, 2023

Contact the study team

• Kelsey Lau-Min, MD, MSCE · Phone: 617-724-4000

Official record on ClinicalTrials.gov — NCT05914766

Locations in the U.S.

Conditions

• Rectal Cancer

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.