Home › Viral Infections › NCT05953233
School Inner City Air Study
Who can join
Ages 6 to 90 · All sexes · Healthy volunteers welcome
Full eligibility criteria
Inclusion Criteria: Children * Grades K-5 (age 6-12 years) * Attend one of the schools that the study team has permission to obtain classroom/school environmental samples * Have no plans to move schools within the upcoming 12 months * Subject and/or parent guardian must be able to understand and provide informed consent and also willing to participate in the study Adults * Adult (age 21 or older) parent, caretaker, or household member of child participating in this study, or teacher in classroom participating in study * Able to understand and provide informed consent Exclusion Criteria: Children * Contraindication to or inability to participate in home self-collection of nasal swab samples * Severe chronic diseases (e.g. cancer, genetic or congenital disorders interfering with mobility) * Severe neurobehavioral, neurodevelopmental or psychiatric disorders requiring special assistance * Families who do not speak English or Spanish well enough to complete the survey questions, as validated versions in other languages are not available for all of the measures Adults * Contraindication to or inability to participate in home self-collection of nasal swab samples * Severe chronic diseases (e.g. cancer, genetic or congenital disorders interfering with mobility) * Severe neurobehavioral, neurodevelopmental or psychiatric disorders requiring special assistance * Families who do not speak English or Spanish well enough to complete the survey questions, as validated versions in other languages are not available for all of the measures
About the study
The goal of this randomized clinical trial is to test the efficacy of high efficiency particulate air (HEPA) cleaners in reducing respiratory viral exposure and infections in elementary school classrooms. Classrooms will be randomized to active vs. sham HEPA cleaners. The main questions it aims to answer are:
* Do classroom HEPA cleaners reduce exposure to viruses? * Do classroom HEPA cleaners reduce student and teacher infections? * Do classroom HEPA cleaners reduce infections in family members?
What is being tested
- Active classroom HEPA cleaner (other)
- Sham classroom HEPA cleaner (other)
Sponsor: Massachusetts General Hospital · Participants: 200 · Started: Sep 15, 2024
Contact the study team
- Peggy Lai, MD MPH · Phone: 617-875-9878
- Wanda Phipatanakul, MD MS · Phone: 857-218-5336
Official record on ClinicalTrials.gov — NCT05953233
Locations in the U.S.
| Massachusetts | Mass General Brigham, Boston |
Conditions
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.