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Lifestyle Intervention for Healthy Change
Healthy Living: Incorporating Lifestyle Interventions to Encourage a Reduction in Body Weight.
Who can join
Ages 18 to 40 · All sexes · Healthy volunteers welcome
Full eligibility criteria
Inclusion Criteria: * Age 18-40 years * BMI \> 25 kg/m2 * No cardiopulmonary disease * stable on medications for 3 months * weight stable (+/-5 pounds) for the past 3 months * Not pregnant or trying to get pregnant * Owns a smartphone * Able to walk unassisted * Not on supplemental oxygen Exclusion Criteria: * Under the age of 18 years * 40 years and older * Unable to participate in an exercise program * Currently pregnant
About the study
The purpose of this study is to determine the effectiveness of a physician led, multi-disciplinary approach to treating obesity that incorporates nutrition (mainly, using genetics to identify appropriate food intake), exercise, and motivational counseling. The investigators plan to recruit overweight/obese (BMI\>25) males and females to participate. Participants will be randomized to receive a personalized diet plan, or a standard care diet plan; both groups will participate in the exercise intervention. For a 6-month duration, both groups will be asked to improve their diet according to their dietary plan and participate in moderate-to-vigorous physical activity (gradual increase up to 300 min/week). The investigators intend to evaluate standard outcomes of weight loss, and assess for any predictors of positive outcomes. Following the six-month intervention, participants will complete a 3-month no contact phase. This no contact phase will provide insight into the effects of the study on weight loss maintenance. Our team also plans to address acceptability by providing evaluations to study participants and conducting interviews with a small subset of participants to improve the intervention for the future.
What is being tested
- Nutrigenomix, personalized dietary plan (behavioral)
- Physical Activity (behavioral)
- Behavioral counseling (behavioral)
- Standard Dietary plan (behavioral)
Sponsor: Augusta University · Participants: 125 · Started: 2025-04
Contact the study team
- Madison Kindred, PhD · Phone: 774-238-0591
Official record on ClinicalTrials.gov — NCT05956574
Locations in the U.S.
| Georgia | Augusta University, Augusta |
Conditions
From ClinicalTrials.gov, data retrieved Oct 2, 2026. Each study sets its own eligibility; the study team decides who can join.