A Study of Breath Testing for Small Intestinal Bacterial Overgrowth
Recruiting
Breath Testing for Small Intestinal Bacterial Overgrowth in Patients Treated With Proton Pump Inhibitors
Who can join
Ages 18 and older · All sexes
Full eligibility criteria
Inclusion criteria: * Predominant symptoms of gastroesophageal reflux disease including heartburn, regurgitation * Subjects must be able to give appropriate informed consent Exclusion criteria: * Prior diagnosis of SIBO * Use of PPIs or H2R-anatagonstists in the prior 3 months * Major concomitant illness (renal, hepatic, rheumatologic or cardiovascular disease, or malignancy) * Antibiotic therapy within one month * Prior gastrointestinal surgery including esophageal, gastric, and small or large bowel surgery * Previously diagnosed irritable bowel syndrome or inflammatory bowel disease * Individuals who are pregnant or breast feeding * Patients with plans to become pregnant * Inability to take PPIs, including allergy/sensitivity
About the study
Researchers hope to determine how often small intestinal bacterial overgrowth occurs after taking proton pump inhibitors.
What is being tested
- Breath Testing (other)
Sponsor: Mayo Clinic · Participants: 50 · Started: Nov 17, 2023
Contact the study team
Official record on ClinicalTrials.gov — NCT05976165
Locations in the U.S.
| Florida | Mayo Clinic Florida, Jacksonville |
Conditions
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.