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GERD clinical trials recruiting in the U.S.
36 studies for GERD are recruiting participants at sites across the United States.
Gastroesophageal reflux disease (GERD) is a chronic condition that can cause discomfort and lead to other health problems. Its most common symptom is heartburn.
Cities with the most studies
- Kansas City, MO5 studies
- Milwaukee, WI3 studies
- Chicago, IL3 studies
- Rochester, MN3 studies
- Indianapolis, IN3 studies
- Cleveland, OH3 studies
- Baltimore, MD3 studies
By state
- California4 studies
- Colorado4 studies
- Illinois3 studies
- Indiana3 studies
- Maryland3 studies
- Minnesota4 studies
- Missouri5 studies
- New York5 studies
- Ohio3 studies
- Pennsylvania3 studies
- Wisconsin4 studies
Recently updated studies
Multi-Site Detection of Barrett's Esophagus in Patients Without Chronic GERD Symptoms
RecruitingHealthy volunteers welcome
Ages 50 and older · All sexes · Updated Sep 15, 2026 · NCT06687603Abbott Cephea Mitral Valve Disease Registry
RecruitingObservational study
Ages 18 and older · All sexes · Updated Sep 10, 2026 · NCT07069673Gastrointestinal Dysmotility on Aspiration Risk
RecruitingPhase 4
Ages 5 to 21 · All sexes · Updated Aug 3, 2026 · NCT05455359Utility of Mucosal Impedance Device in Chronic Esophageal Disorders:
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Jul 27, 2026 · NCT07227506Transventricular Off-pump Mitral Valve Repair
Recruiting
Ages 21 and older · All sexes · Updated Jul 24, 2026 · NCT07726173Transpyloric Versus Gastric Feeding in Bronchopulmonary Dysplasia
Recruiting
1 Month – 12 Months · All sexes · Updated Jul 17, 2026 · NCT06534359Mechanistic and Clinical Outcomes of a Surgical Innovation Aimed at Minimizing GERD Associated With VSG (INNOVATE-VSG)
Recruiting
Ages 18 to 65 · All sexes · Updated Jul 14, 2026 · NCT06783751The Effect of the Reflux Band™ Upper Esophageal Sphincter (UES) Assist Device on Reflux for Lung Transplant Recipients
Recruiting
Ages 18 to 80 · All sexes · Updated Jul 13, 2026 · NCT03886961Randomized Controlled Crossover Trial of Postpyloric Feedings to Improve Pulmonary Outcomes in High-risk Preterm Infants
Recruiting
0 Hours – 1 Year · All sexes · Updated Jun 29, 2026 · NCT05777512Safety and Effectiveness of eGERD Device to Reduce Gastroesophageal Reflux Disease (GERD) Symptoms
Recruiting
Ages 22 to 75 · All sexes · Updated Jun 23, 2026 · NCT06613438GI Neuromuscular Pathology Prospective Registry
RecruitingObservational studyHealthy volunteers welcome
6 Months – 90 Years · All sexes · Updated Jun 16, 2026 · NCT02165059Indiana University Gastrointestinal Motility Diagnosis Registry
RecruitingObservational study
All ages · All sexes · Updated Jun 16, 2026 · NCT04506593Famotidine and Antacids for Treatment of Dyspepsia
RecruitingPhase 4
Ages 18 and older · All sexes · Updated Jun 2, 2026 · NCT06241183Esophageal and Gastric Registry and Biorepository
RecruitingObservational studyHealthy volunteers welcome
Ages 18 to 85 · All sexes · Updated May 4, 2026 · NCT05180253Endoscopic Bariatric Therapies (EBTs): A Retrospective and Prospective Multicenter Registry
RecruitingObservational study
Ages 18 to 89 · All sexes · Updated Apr 23, 2026 · NCT04494048Esophageal Cancer Risk Registry
RecruitingObservational study
Ages 18 and older · All sexes · Updated Apr 14, 2026 · NCT00260585Compassionate Use of Domperidone for Refractory Gastroparesis
Recruiting
Ages 12 to 21 · All sexes · Updated Mar 24, 2026 · NCT04699591Clinical Utility of WATS3D: A 5-Year Prospective Study
RecruitingObservational study
Ages 18 and older · All sexes · Updated Mar 20, 2026 · NCT04312633Implementing Virtual Reality (VR) to Reduce Sedation
RecruitingHealthy volunteers welcome
Ages 21 to 65 · All sexes · Updated Mar 19, 2026 · NCT06349564External UES Band (Shaker Pressure Band) and GERD
Recruiting
Ages 18 to 85 · All sexes · Updated Mar 9, 2026 · NCT05697393Post-sleeve Gastrectomy Gastroesophageal Reflux Disease Prediction
Recruiting
Ages 18 and older · All sexes · Updated Mar 5, 2026 · NCT04411823Anti-Reflux Endoscopic TX Using APC (AREA) in GERD Patients: (The AREA Study)
Recruiting
Ages 18 to 80 · All sexes · Updated Feb 27, 2026 · NCT05570448A Study of Breath Testing for Small Intestinal Bacterial Overgrowth
Recruiting
Ages 18 and older · All sexes · Updated Feb 12, 2026 · NCT05976165Mechanisms Preventing Pharyngeal Reflux
RecruitingHealthy volunteers welcome
Ages 18 to 85 · All sexes · Updated Feb 10, 2026 · NCT05696184Efficacy Of Hiatal Closure For GERD
RecruitingObservational study
Ages 18 to 50 · All sexes · Updated Feb 2, 2026 · NCT06280664From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.