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QL Block in Laparoscopic Myomectomy

Quadratus Lumborum Block to Improve Postoperative Pain Management After Laparoscopic Myomectomies: a Double-blinded and Prospective Randomized Clinical Trial.

Who can join

Ages 18 to 45 · Women

Inclusion Criteria:

* Presence of uterine fibroids requiring surgical excision with preservation of the uterus
* Stated willingness to comply with all study procedures and availability for the duration of the study
* Provision of signed and dated informed consent form

Exclusion Criteria:

* Pre-existing diagnoses of anxiety or depression
* Pre-existing coagulopathies
* Pre-existing neuropathic or chronic pelvic pain
* Chronic opioid use
* Illiteracy due to inability to read and understand plain questionnaire
* Non-English speaking
* BMI \>38

About the study

This study aims to determine the efficacy of a quadratus lumborum (QL) block in decreasing postoperative pain in patients undergoing myomectomy for uterine fibroids. A QL block is a temporary anesthetic injection in the quadratus lumborum muscle, a muscle in the lower back, that has been previously shown to significantly reduce postoperative pain levels in patients undergoing abdominal and pelvic surgery. Because of its demonstrated effects, the QL block is becoming a standard of anesthesia and surgical care. Since participants will be undergoing a myomectomy procedure, the investigators believe that participants may qualify to participate in this study. The investigators will be comparing patients who receive the QL block (in addition to standard anesthesia and postoperative pain care) with patients who do not receive the QL block (in addition to standard care). The participants will be randomly assigned to one of the two groups and may or may not actually receive the block.

What is being tested

• Bupivacain (drug)
• Saline (drug)

Sponsor: Joseph Findley MD · Participants: 80 · Started: Aug 24, 2024

Contact the study team

• Catherine P Haering, BA · Phone: 3392011531

Official record on ClinicalTrials.gov — NCT05979493

Locations in the U.S.

Conditions

• Pain After Surgery
• Uterine Fibroids

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.