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Enhancing Memory in Cognitive Processing Therapy for PTSD
Enhancing Memory in Cognitive Processing Therapy for Older Adults With PTSD
Who can join
Ages 60 and older · All sexes
Full eligibility criteria
Inclusion Criteria: * Veterans with DSM-5 diagnoses of PTSD via the Clinician Administered PTSD Scale (CAPS-5) Exclusion Criteria: * daily benzodiazepine use (due to memory impairing effects) * bipolar or psychotic disorders * current suicidal ideation with plan or intent * current moderate or severe substance use disorder not in remission for \>1 month * severe traumatic brain injury * a Montreal Cognitive Assessment (MoCA) indicative of dementia * or other disorders that would severely limit study participation
About the study
Several psychotherapies for posttraumatic stress disorder (PTSD) have a strong evidence base for their efficacy, but nonresponse rates are high, particularly among older Veterans. Accumulating evidence indicates that memory deficits and poor learning of therapy contents adversely affect psychotherapy treatment response in PTSD. However, limited research has examined methods for increasing learning of therapy contents in psychotherapy for PTSD. The proposed study aims to examine the feasibility of integrating an intervention to increase learning and memory of psychotherapy content into the provision of a widely used psychotherapy, cognitive processing therapy (CPT), for older adults with PTSD. The ultimate goal of this line of research is to develop novel rehabilitation interventions to increase functioning for individuals with PTSD.
What is being tested
- Cognitive Processing Therapy (behavioral)
- Cognitive Processing Therapy (CPT) + Memory Support (behavioral)
Sponsor: VA Office of Research and Development · Participants: 30 · Started: Oct 15, 2024
Contact the study team
- James C Scott, PhD · Phone: (215) 823-5800
- Richard A Moore · Phone: (215) 823-5800
Official record on ClinicalTrials.gov — NCT06000475
Locations in the U.S.
| Pennsylvania | Corporal Michael J. Crescenz VA Medical Center, Philadelphia, PA, Philadelphia |
Conditions
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.