Does Nerve Block + Oral Dexamethasone Reduce Recurrence of Headache Within 72 Hrs?
Does Nerve Block Plus Oral Dexamethasone Reduce Recurrence of Headache Within 72 Hours Better Than Nerve Block Alone?
Who can join
Ages 18 to 85 · All sexes
Full eligibility criteria
Inclusion Criteria: * Meet ICHD-3 Migraine Headache Criteria * Had a minimum 5-point reduction in headache intensity after nerve block(s) or post- block pain score of 0 to 2 * Nerve block performed with bupivacaine 0.5% Exclusion Criteria: * Head trauma * Suspicion of secondary headache (i.e. stroke, known tumor, glaucoma) * Headache in the setting of viral syndrome * Chronically on steroids * Known allergy to dexamethasone * Unable to reach the patient by phone or text for follow-up * Gestational diabetes or other uncontrolled diabetes * Known to be immunocompromised
About the study
For some patients who come to the emergency department for treatment of a migraine headache, peripheral headache nerve blocks (PHNB) have proven to be an efficient and effective treatment for headache relief. Previous studies have demonstrated that adding steroids as an adjunct treatment to standard migraine treatment can reduce recurrence of headaches in the subsequent few days.
What is being tested
- Dexamethasone Oral (drug)
- Placebo (drug)
Sponsor: Texas Tech University Health Sciences Center, El Paso · Participants: 84 · Started: Sep 15, 2023
Contact the study team
- Edward Michelson, MD · Phone: 915 215 4600
Official record on ClinicalTrials.gov — NCT06016465
Locations in the U.S.
| Texas | University Medical Center of El Paso, El Paso |
Conditions
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.