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Friedreich Ataxia Global Clinical Consortium UNIFIED Natural History Study

RecruitingObservational studyHealthy volunteers welcome

Who can join

All ages · All sexes · Healthy volunteers welcome

Full eligibility criteria
Inclusion Criteria:

1. Both males and females of any age
2. Individuals with Friedreich ataxia (FA): Participants that meet genetically confirmed diagnosis of Friedreich ataxia
3. Written informed consent provided

   1. Informed consent must be obtained for all participants
   2. For underage participants, they and the parent/ legally authorized representative have to sign the informed consent form, child assent (if applicable)
   3. Persons who are not legally competent require the informed consent of their legally authorized representative

   Exclusion Criteria:
4. Unable or unwilling to provide informed consent
5. Acute or ongoing medical or other conditions that would interfere with the conduct and assessments of the study
6. For any reason in the opinion of the investigator, participant would be unlikely or unable to comply with study protocol requirements.

About the study

This project is a global, multicenter, prospective, longitudinal, observational natural history study that can be used to understand the disease progression and support the development of safe and effective drugs and biological products for Friedreich ataxia.

Sponsor: Friedreich's Ataxia Research Alliance · Participants: 3,000 · Started: Jun 28, 2023

Contact the study team

Official record on ClinicalTrials.gov — NCT06016946

Locations in the U.S.

CaliforniaUCLA Ataxia Center, Los Angeles
ColoradoUniversity of Colorado, Denver
FloridaUniversity of Florida - Neurology, Gainesville
USF Ataxia Research Center, Tampa
GeorgiaEmory University Hospital - Neurology, Atlanta
IowaUniversity of Iowa, Stead Family Children's Hospital, Iowa City
OhioOhio State University - Neurology, Columbus
PennsylvaniaChildren's Hospital of Philadelphia, Philadelphia
TennesseeSt. Jude Children's Research Hospital, Memphis

Conditions

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.