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Opioid-Free Pain Treatment in Trauma Patients

Recruiting

Peri-operative Opioid-free Analgesic Protocol for Orthopedic Trauma Patients

Who can join

Ages 18 and older · All sexes

Full eligibility criteria
Inclusion Criteria:

* Patient is over the age of 18 years old
* Underwent surgical treatment for the injuries of interest (stated elsewhere) by an Orthopedic Traumatology Attending Physician at the University of Kansas Hospital

Exclusion Criteria:

* Patients that are unable to provide informed consent due to sustaining a head injury or incoherence from narcotics given to them post-injury
* Chronic opioid use
* Under the age of 18 years old
* Undergoing revision surgery
* Did not undergo surgical fixation
* Pregnant/nursing women
* Vulnerable populations as defined by the University of Kansas Medical Center IRB
* Did not experience one of the following fractures listed in D.1. above.
* Patients with CKD and/or cirrhosis will be excluded from the opioid-free pain block (block 2) and will only qualify for the standard of care opioid group (Block 1)

About the study

Analgesic drug study that will compare pain outcomes of opioid analgesia and opioid-free analgesia in post-operative orthopedic patients.

What is being tested

Sponsor: University of Kansas Medical Center · Participants: 250 · Started: Nov 1, 2023

Contact the study team

Official record on ClinicalTrials.gov — NCT06078371

Locations in the U.S.

KansasThe University of Kansas Medical Center, Kansas City

Conditions

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.