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Performance of New Diagnostic Methods in Older Adults With Pneumonia

RecruitingObservational study

Establishing and Implementing Pneumonia Diagnosis in ED Older Adults: A Mixed Methods Approach

Who can join

Ages 65 and older · All sexes

Full eligibility criteria
Inclusion Criteria:

\- Adults aged 65 and older presenting to the ED with suspected pneumonia defined as (1) either a physician order for CXR OR CT OR a chief complaint consistent with dyspnea; AND (2) physician suspicion of pneumonia prior to ED testing (score of 2-5 on Likert scale)

Exclusion Criteria:

* inability to obtain consent from the patient or an LAR
* active cancer
* organ transplant
* immunosuppression
* trauma activation
* suicidal ideation
* incarceration
* antibiotics in the last 14 days
* a separate episode of lower respiratory illness in the last 30 days

About the study

Create a clinical diagnostic pathway for older ED adults with pneumonia and its subgroups (bacterial, viral, and co-infection) and determine whether novel biomarkers improve diagnostic accuracy. The investigators will conduct a prospective observational trial of 250 ED patients ≥65 years old with suspected pneumonia. The investigators will perform analyses overall and by subgroups, seeking common models to ease adoption.

Sponsor: Ohio State University · Participants: 250 · Started: Dec 2, 2022

Contact the study team

Official record on ClinicalTrials.gov — NCT06092008

Locations in the U.S.

OhioThe Ohio State University, Columbus

Conditions

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.