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Pneumonia clinical trials recruiting in the U.S.
31 studies for Pneumonia are recruiting participants at sites across the United States.
Pneumonia is an infection in one or both of the lungs. Symptoms of pneumonia vary to mild to severe. Read about the signs of pneumonia.
Cities with the most studies
- Houston, TX8 studies
- Salt Lake City, UT6 studies
- Chicago, IL6 studies
- Washington, DC5 studies
- Durham, NC5 studies
- St. Louis, MO4 studies
- Dallas, TX4 studies
- Hialeah, FL4 studies
- Atlanta, GA4 studies
- Philadelphia, PA4 studies
- Los Angeles, CA4 studies
- New York City, NY4 studies
- Boston, MA4 studies
- Cincinnati, OH4 studies
- Cleveland, OH3 studies
- New Orleans, LA3 studies
- Charleston, SC3 studies
- San Diego, CA3 studies
- Miami, FL3 studies
- Seattle, WA3 studies
- Baltimore, MD3 studies
- Boise, ID3 studies
- Worcester, MA3 studies
- Ann Arbor, MI3 studies
- San Francisco, CA3 studies
- Mountain View, CA3 studies
- Columbus, OH3 studies
By state
- California12 studies
- Colorado3 studies
- District of Columbia3 studies
- Florida7 studies
- Georgia6 studies
- Idaho3 studies
- Illinois7 studies
- Kentucky3 studies
- Louisiana4 studies
- Maryland6 studies
- Massachusetts5 studies
- Michigan4 studies
- Missouri6 studies
- New Jersey4 studies
- New York7 studies
- North Carolina6 studies
- Ohio10 studies
- Pennsylvania9 studies
- South Carolina4 studies
- Tennessee4 studies
- Texas9 studies
- Utah7 studies
- Washington3 studies
Recently updated studies
Natural History, Management, and Genetics of the Hyperimmunoglobulin E Recurrent Infection Syndrome (HIES)
RecruitingObservational studyHealthy volunteers welcome
1 Month โ 120 Years ยท All sexes ยท Updated Nov 12, 2026 ยท NCT00006150Optimizing Medications and Lung Health in People With HIV Through Pharmacist-led Proactive E-Consults
Recruiting
Ages 18 and older ยท All sexes ยท Updated Nov 9, 2026 ยท NCT07507435Randomized, Embedded, Multifactorial Adaptive Platform Trial for Community- Acquired Pneumonia
RecruitingPhase 3
28 Days ยท All sexes ยท Updated Nov 4, 2026 ยท NCT02735707A Study to Learn About a Study Medicine Called Ibuzatrelvir in Adult and Adolescent Patients With COVID-19 Who Are Not Hospitalized But Are at Risk For Severe Disease
RecruitingPhase 3
Ages 12 and older ยท All sexes ยท Updated Oct 15, 2026 ยท NCT06679140A Study to Learn About the Study Medicine Ibuzatrelvir in Adults With COVID-19 Who Are Severely Immunocompromised
RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Oct 14, 2026 ยท NCT07013474Study of Lung Proteins in Patients With Pneumonia
RecruitingObservational study
Ages 3 to 99 ยท All sexes ยท Updated Oct 13, 2026 ยท NCT00077909AntiThrombotic Therapy to Ameliorate Clinical Complications in Community Acquired Pneumonia
RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Sep 30, 2026 ยท NCT05848713A Study of COVID-19 Vaccine(s) in Children and Adults
RecruitingPhase 3Healthy volunteers welcome
Ages 5 and older ยท All sexes ยท Updated Sep 28, 2026 ยท NCT07798648Hyperpolarized 129-Xenon Imaging in Adult Hematopoietic Cell Transplant Recipients With Pulmonary Impairment
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older ยท All sexes ยท Updated Aug 25, 2026 ยท NCT05041140Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)
RecruitingObservational studyHealthy volunteers welcome
Ages 0 to 20 ยท All sexes ยท Updated Aug 21, 2026 ยท NCT04278404How OMT Benefits Newly Diagnosed Patients With Respiratory Illness When Given Alongside Other Standard Care.
Recruiting
Ages 65 to 100 ยท All sexes ยท Updated Aug 11, 2026 ยท NCT06495021A Study to Learn About a COVID-19 Vaccine in Healthy Adults 18 Through 64 Years of Age
RecruitingPhase 4Healthy volunteers welcome
Ages 18 to 64 ยท All sexes ยท Updated Aug 7, 2026 ยท NCT07730450The Effects of Endotracheal Suctioning on Pain and Serum Markers
Recruiting
Ages 18 and older ยท All sexes ยท Updated Jul 10, 2026 ยท NCT06692400A Clinical Trial to Evaluate agenT-797 Plus Standard of Care in Participants With Severe Pneumonia With Moderate to Severe Acute Hypoxemic Respiratory Failure
RecruitingPhase 2
Ages 18 and older ยท All sexes ยท Updated Jun 26, 2026 ยท NCT07615010iNO300 Therapy in Critically Ill Patients With Pneumonia
RecruitingEarly phase 1
Ages 18 and older ยท All sexes ยท Updated May 22, 2026 ยท NCT06950294A Study to Learn About How 20-Valent Pneumococcal Conjugate Vaccine Works in a Real-world Setting
RecruitingObservational study
Ages 65 and older ยท All sexes ยท Updated May 11, 2026 ยท NCT05452941PET Imaging CCR2 in Lung Inflammation
RecruitingEarly phase 1Healthy volunteers welcome
Ages 21 and older ยท All sexes ยท Updated May 1, 2026 ยท NCT03492762Incentive Spirometry to Improve Outcomes in Lung Cancer Patients Undergoing Concurrent Chemotherapy and Radiation Therapy
Recruiting
Ages 18 and older ยท All sexes ยท Updated Apr 15, 2026 ยท NCT06688422Lung Ultrasound for Guiding Antibiotic Use in Pediatric Pneumonia
Recruiting
Ages 3 to 10 ยท All sexes ยท Updated Apr 3, 2026 ยท NCT06921993Immune Defense Protein Impact On Respiratory Immune Outcomes
RecruitingHealthy volunteers welcome
Ages 60 and older ยท All sexes ยท Updated Mar 12, 2026 ยท NCT07431840The APS Phenotyping Study
RecruitingObservational study
Ages 18 and older ยท All sexes ยท Updated Feb 20, 2026 ยท NCT06521502The Role of Circadian Clock Proteins in Innate and Adaptive Immunity
Recruiting
Ages 18 to 65 ยท All sexes ยท Updated Feb 11, 2026 ยท NCT03482245Performance of New Diagnostic Methods in Older Adults With Pneumonia
RecruitingObservational study
Ages 65 and older ยท All sexes ยท Updated Feb 6, 2026 ยท NCT06092008Comparing Antibiotic Treatment Strategies for Children With Pneumonia in Outpatient Settings: (STAMPP)
Recruiting
12 Months โ 71 Months ยท All sexes ยท Updated Jan 27, 2026 ยท NCT06986148Reducing Overuse of Antibiotics With Decision Support
Recruiting
6 Months โ 17 Years ยท All sexes ยท Updated Jan 22, 2026 ยท NCT06788093From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.