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Pneumonia clinical trials recruiting in the U.S.

31 studies for Pneumonia are recruiting participants at sites across the United States.

Pneumonia is an infection in one or both of the lungs. Symptoms of pneumonia vary to mild to severe. Read about the signs of pneumonia.

Cities with the most studies

By state

Recently updated studies

A Study of COVID-19 Vaccine(s) in Children and Adults

RecruitingPhase 3Healthy volunteers welcome
Ages 5 and older ยท All sexes ยท Updated Sep 28, 2026 ยท NCT07798648

Natural History, Management, and Genetics of the Hyperimmunoglobulin E Recurrent Infection Syndrome (HIES)

RecruitingObservational studyHealthy volunteers welcome
1 Month โ€“ 120 Years ยท All sexes ยท Updated Sep 28, 2026 ยท NCT00006150

A Study to Learn About the Study Medicine Ibuzatrelvir in Adults With COVID-19 Who Are Severely Immunocompromised

RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Sep 25, 2026 ยท NCT07013474

Study of Lung Proteins in Patients With Pneumonia

RecruitingObservational study
Ages 3 to 99 ยท All sexes ยท Updated Sep 22, 2026 ยท NCT00077909

Hyperpolarized 129-Xenon Imaging in Adult Hematopoietic Cell Transplant Recipients With Pulmonary Impairment

RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older ยท All sexes ยท Updated Aug 25, 2026 ยท NCT05041140

Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)

RecruitingObservational studyHealthy volunteers welcome
Ages 0 to 20 ยท All sexes ยท Updated Aug 21, 2026 ยท NCT04278404

How OMT Benefits Newly Diagnosed Patients With Respiratory Illness When Given Alongside Other Standard Care.

Recruiting
Ages 65 to 100 ยท All sexes ยท Updated Aug 11, 2026 ยท NCT06495021

A Study to Learn About a COVID-19 Vaccine in Healthy Adults 18 Through 64 Years of Age

RecruitingPhase 4Healthy volunteers welcome
Ages 18 to 64 ยท All sexes ยท Updated Aug 7, 2026 ยท NCT07730450

The Effects of Endotracheal Suctioning on Pain and Serum Markers

Recruiting
Ages 18 and older ยท All sexes ยท Updated Jul 10, 2026 ยท NCT06692400

iNO300 Therapy in Critically Ill Patients With Pneumonia

RecruitingEarly phase 1
Ages 18 and older ยท All sexes ยท Updated May 22, 2026 ยท NCT06950294

A Study to Learn About How 20-Valent Pneumococcal Conjugate Vaccine Works in a Real-world Setting

RecruitingObservational study
Ages 65 and older ยท All sexes ยท Updated May 11, 2026 ยท NCT05452941

PET Imaging CCR2 in Lung Inflammation

RecruitingEarly phase 1Healthy volunteers welcome
Ages 21 and older ยท All sexes ยท Updated May 1, 2026 ยท NCT03492762

AntiThrombotic Therapy to Ameliorate Clinical Complications in Community Acquired Pneumonia

RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Apr 21, 2026 ยท NCT05848713

Incentive Spirometry to Improve Outcomes in Lung Cancer Patients Undergoing Concurrent Chemotherapy and Radiation Therapy

Recruiting
Ages 18 and older ยท All sexes ยท Updated Apr 15, 2026 ยท NCT06688422

Lung Ultrasound for Guiding Antibiotic Use in Pediatric Pneumonia

Recruiting
Ages 3 to 10 ยท All sexes ยท Updated Apr 3, 2026 ยท NCT06921993

Immune Defense Protein Impact On Respiratory Immune Outcomes

RecruitingHealthy volunteers welcome
Ages 60 and older ยท All sexes ยท Updated Mar 12, 2026 ยท NCT07431840

The APS Phenotyping Study

RecruitingObservational study
Ages 18 and older ยท All sexes ยท Updated Feb 20, 2026 ยท NCT06521502

The Role of Circadian Clock Proteins in Innate and Adaptive Immunity

Recruiting
Ages 18 to 65 ยท All sexes ยท Updated Feb 11, 2026 ยท NCT03482245

Performance of New Diagnostic Methods in Older Adults With Pneumonia

RecruitingObservational study
Ages 65 and older ยท All sexes ยท Updated Feb 6, 2026 ยท NCT06092008

Comparing Antibiotic Treatment Strategies for Children With Pneumonia in Outpatient Settings: (STAMPP)

Recruiting
12 Months โ€“ 71 Months ยท All sexes ยท Updated Jan 27, 2026 ยท NCT06986148

Reducing Overuse of Antibiotics With Decision Support

Recruiting
6 Months โ€“ 17 Years ยท All sexes ยท Updated Jan 22, 2026 ยท NCT06788093

Cough Capture as a Portal Into the Lung

RecruitingObservational study
Ages 21 and older ยท All sexes ยท Updated Jan 13, 2026 ยท NCT05854563

Follow-up Automatically vs. As-Needed Comparison (FAAN-C) Trial

Recruiting
Up to age 18 ยท All sexes ยท Updated Dec 10, 2025 ยท NCT05471908

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.