A Clinical Trial of Adaptive Treatment for Early Smoking Cessation Relapse
Who can join
Ages 21 and older · All sexes · Healthy volunteers welcome
Full eligibility criteria
Inclusion Criteria: * Smokers who want to quit Exclusion Criteria: * Non-smokers
About the study
This is a research study to find out if treatment decision making can be improved for smokers who find it difficult to quit with medications. Everyone who participates in this study will receive free product, either nicotine replacement therapies (patches and lozenges), varenicline, or a harm reduction product (e-cigarette) for a full 12 weeks. Most participants will receive some combination of these treatments, depending on individual response to each.
All visits and study assessments will be entirely remote. All treatments will be provided free of charge for the first 12 weeks. After that, the study team will contact the participants 6 months after the first study phone call to complete another survey. The study lasts six months and will involve 8 surveys.
What is being tested
- Switching to a different medication (behavioral)
- Continued use of the same medication (behavioral)
- Switching to a harm reduction tobacco product (behavioral)
Sponsor: Medical University of South Carolina · Participants: 544 · Started: Mar 25, 2024
Contact the study team
- Tracy T Smith, PhD · Phone: 8438725164
- Matthew J Carpenter, PhD · Phone: 8438762436
Official record on ClinicalTrials.gov — NCT06118502
Locations in the U.S.
| South Carolina | Medical University of South Carolina, Charleston |
Conditions
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.