๐Ÿ”Ž Trials Near Me

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Smoking clinical trials recruiting in the U.S.

52 studies for Smoking are recruiting participants at sites across the United States.

There's no way around it. Smoking is bad for your health. Learn the effects of smoking (how smoking harms nearly every organ) and how to quit.

Cities with the most studies

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Recently updated studies

Imaging Sex Differences in Smoking-Induced Pulmonary Inflammation

RecruitingPhase 1Healthy volunteers welcome
Ages 18 to 45 ยท All sexes ยท Updated Sep 24, 2026 ยท NCT03721822

Empowering Patients' Lung Cancer Screening Uptake (Empower LCS/Call+)

Recruiting
Ages 50 to 80 ยท All sexes ยท Updated Sep 21, 2026 ยท NCT07711691

Semaglutide for Post-Smoking Cessation Weight Management

RecruitingPhase 2Healthy volunteers welcome
Ages 18 to 75 ยท All sexes ยท Updated Sep 21, 2026 ยท NCT06173778

Trauma-Informed Care for Smoking Cessation for Pregnancy

RecruitingHealthy volunteers welcome
Ages 18 and older ยท Women ยท Updated Sep 10, 2026 ยท NCT07129590

Varenicline for Smoking Reduction in Veterans Not Ready To Quit

RecruitingPhase 4
Ages 21 and older ยท All sexes ยท Updated Aug 31, 2026 ยท NCT06966362

Cardiovascular Effects of Very Low Nicotine Content Cigarettes

RecruitingEarly phase 1Healthy volunteers welcome
Ages 21 and older ยท All sexes ยท Updated Aug 28, 2026 ยท NCT05707871

A Study Evaluating the Use of an Indoor Air Quality Monitor to Promote a Smoke-free Home

RecruitingHealthy volunteers welcome
Ages 18 and older ยท All sexes ยท Updated Aug 27, 2026 ยท NCT06693700

Evaluation of Low and High Nicotine Tobacco Free Nicotine Pouches

RecruitingHealthy volunteers welcome
Ages 21 and older ยท All sexes ยท Updated Aug 20, 2026 ยท NCT06678789

The SMOKE Telehealth Study

Recruiting
Ages 18 and older ยท All sexes ยท Updated Aug 12, 2026 ยท NCT07743710

A Clinical Trial of Adaptive Treatment for Early Smoking Cessation Relapse

RecruitingHealthy volunteers welcome
Ages 21 and older ยท All sexes ยท Updated Aug 12, 2026 ยท NCT06118502

Effects of Cannabidiol on Stress and Nicotine Withdrawal

RecruitingPhase 1
Ages 21 to 70 ยท All sexes ยท Updated Aug 10, 2026 ยท NCT07001930

Maternal Smoking Cessation and Pediatric Obesity Prevention

RecruitingHealthy volunteers welcome
Ages 18 to 39 ยท Women ยท Updated Jul 30, 2026 ยท NCT03514602

A Multi-Site Study to Assess the Effect of Availability of a Heated Tobacco Product on Smoking Abstinence Among Current Primary Cigarette Smokers

RecruitingHealthy volunteers welcome
Ages 21 to 65 ยท All sexes ยท Updated Jul 17, 2026 ยท NCT07710820

Switch or Quit R01

RecruitingHealthy volunteers welcome
Ages 21 and older ยท All sexes ยท Updated Jul 13, 2026 ยท NCT06373679

5-HT2A Agonist Psilocybin in the Treatment of Tobacco Use Disorder

RecruitingPhase 2Healthy volunteers welcome
Ages 21 and older ยท All sexes ยท Updated Jun 29, 2026 ยท NCT05452772

PASCAL Feasibility Study

Recruiting
Ages 21 and older ยท All sexes ยท Updated Jun 24, 2026 ยท NCT07301151

Prevention of Postpartum Smoking Relapse and Related Health Consequences by Breastfeeding Promotion

RecruitingHealthy volunteers welcome
Ages 18 and older ยท Women ยท Updated Jun 22, 2026 ยท NCT07661550

Catalyzing Cigarette Smoking Cessation Through Harm Reduction Sampling Among People Unmotivated to Quit

RecruitingHealthy volunteers welcome
Ages 21 and older ยท All sexes ยท Updated Jun 11, 2026 ยท NCT07199517

Cigarette Filter Study

Recruiting
Ages 21 and older ยท All sexes ยท Updated Jun 5, 2026 ยท NCT07348679

A Study to Determine the Effects of ENDS Flavor Availability on Abstinence Within Smokers

RecruitingHealthy volunteers welcome
Ages 21 to 65 ยท All sexes ยท Updated Jun 3, 2026 ยท NCT07598136

GLP-1 Receptor Agonists to Decrease Ethanol and CVD Risk in HIV

RecruitingPhase 2
Ages 18 to 89 ยท All sexes ยท Updated May 26, 2026 ยท NCT07221214

Effects of Tax Proposals and Cigarette Availability on Tobacco Purchasing

Recruiting
Ages 21 and older ยท All sexes ยท Updated May 19, 2026 ยท NCT07142668

Breathe Easier With Tadalafil Therapy for Dyspnea in COPD-PH

RecruitingPhase 2
Ages 35 to 89 ยท All sexes ยท Updated May 15, 2026 ยท NCT05937854

Measuring Communal Coping in Dual-smoking Couples Making a Quit Attempt

RecruitingObservational study
Ages 18 and older ยท All sexes ยท Updated May 15, 2026 ยท NCT07553962

From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.