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Aimovig Pregnancy Exposure Registry
RecruitingObservational studyHealthy volunteers welcome
GENESIS: AIMOVIG® Pregnancy Exposure Registry
Who can join
Ages 18 to 99 · Women · Healthy volunteers welcome
Full eligibility criteria
Inclusion Criteria: * Age 18 years or older (at time of signing the informed consent) * Currently pregnant * The outcome of the pregnancy must not be known * Confirmed clinical diagnosis of migraine Exclusion Criteria: * Women currently participating in another investigational device or investigational drug study, currently taking an investigational medicinal product, or having taken an investigational product within 3 months prior to last menstrual period (LMP) or during pregnancy. Other investigational procedures while participating in this study are excluded. * Women exposed to any medications that target the calcitonin gene-related peptide (CGRP) pathway (ie, CGRP monoclonal antibody \[mAb\] or gepants) in the period from 5 half-lives prior to LMP through the end of pregnancy.
About the study
The primary objective of this study is to estimate the proportion of major congenital malformations in infants of women with migraine exposed to erenumab-aooe during pregnancy compared to infants of women with migraine unexposed to erenumeb-aooe.
What is being tested
- erenumab-aooe (drug)
Sponsor: Amgen · Participants: 2,842 · Started: Jan 27, 2021
Contact the study team
- Amgen Call Center · Phone: 866-572-6436
Official record on ClinicalTrials.gov — NCT06150781
Locations in the U.S.
| North Carolina | IQVIA Virtual Site, Durham |
Conditions
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.