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Aimovig Pregnancy Exposure Registry

RecruitingObservational studyHealthy volunteers welcome

GENESIS: AIMOVIG® Pregnancy Exposure Registry

Who can join

Ages 18 to 99 · Women · Healthy volunteers welcome

Full eligibility criteria
Inclusion Criteria:

* Age 18 years or older (at time of signing the informed consent)
* Currently pregnant
* The outcome of the pregnancy must not be known
* Confirmed clinical diagnosis of migraine

Exclusion Criteria:

* Women currently participating in another investigational device or investigational drug study, currently taking an investigational medicinal product, or having taken an investigational product within 3 months prior to last menstrual period (LMP) or during pregnancy. Other investigational procedures while participating in this study are excluded.
* Women exposed to any medications that target the calcitonin gene-related peptide (CGRP) pathway (ie, CGRP monoclonal antibody \[mAb\] or gepants) in the period from 5 half-lives prior to LMP through the end of pregnancy.

About the study

The primary objective of this study is to estimate the proportion of major congenital malformations in infants of women with migraine exposed to erenumab-aooe during pregnancy compared to infants of women with migraine unexposed to erenumeb-aooe.

What is being tested

Sponsor: Amgen · Participants: 2,842 · Started: Jan 27, 2021

Contact the study team

Official record on ClinicalTrials.gov — NCT06150781

Locations in the U.S.

North CarolinaIQVIA Virtual Site, Durham

Conditions

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.