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Preventing Suicidal Behavior With Diverse High-Risk Youth in Acute Care Settings

Recruiting

Who can join

Ages 12 to 24 · All sexes

Full eligibility criteria
Inclusion Criteria:

* Suicide Risk During Acute Care Visit (At least one item must apply: Chief complaint of suicide-related concern, Active suicidal ideation endorsed in past 1 month on validated suicide screener, Suicidal behavior in the past 3 months on validated suicide screener, and/or Clinician indicated SI in past month or SA in past 3 months).
* Have access to a cellular phone with the ability to receive phone calls and text messages over the 12-month follow- up period
* Adolescent must be verbally fluent and can communicate, understand, and read in either English or Spanish
* Adolescent has been/will be discharged from a higher level of care (i.e. inpatient, day hospital, partial hospitalization program (PHP), or residential treatment program) and back in the community within 4 weeks of the acute care visit.

Exclusion Criteria:

* Significant cognitive or developmental delays that prevent understanding or using SPI+ or IPT-A-SCI (includes inability to communicate verbally)
* Altered mental status (acute psychosis, intoxication, or mania)
* Unable or unwilling to provide informed consent (adults), assent (minors), or permission (parents/caregivers)
* The services offered through the study are not in the best clinical interest of the patient (e.g., presenting problem requires a different level of care or treatment approach).

About the study

This multisite randomized controlled trial will compare two brief interventions for youth and young adults ages 12-24 following an acute care visit for suicide risk: the Stanley-Brown Safety Planning Intervention with follow-up contacts (SPI+) and Interpersonal Psychotherapy for Adolescents-Ultra Short Crisis Intervention (IPT-A SCI). The study will evaluate which approach is more effective in reducing suicidal ideation and suicide events. Findings will help patients, families, and clinicians make informed decisions about care following a suicide-related emergency department visit.

What is being tested

Sponsor: Johns Hopkins University · Participants: 484 · Started: Mar 15, 2025

Contact the study team

Official record on ClinicalTrials.gov — NCT06151158

Locations in the U.S.

FloridaJohns Hopkins All Children's Hospital, St. Petersburg
MarylandJohns Hopkins University, Baltimore
New YorkColumbia University Irving Medical Center (CUMC), New York
Weill-Cornell Medicine, New York
North CarolinaUniversity of North Carolina Medical Center, Chapel Hill
PennsylvaniaChildrens Hospital of Philadelphia, Philadelphia

Conditions

From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.