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Suicide clinical trials recruiting in the U.S.

114 studies for Suicide are recruiting participants at sites across the United States.

Suicide is the tenth most common cause of death in the United States. Read about the causes and treatment available, including a suicide hotline number

Cities with the most studies

By state

Recently updated studies

Integrated Suicide Supports and Safety Planning for Youth

Recruiting
Ages 13 to 21 ยท All sexes ยท Updated Nov 13, 2026 ยท NCT06701006

National Sponsorship Program for Transitioning Service Members

RecruitingHealthy volunteers welcome
Ages 18 and older ยท All sexes ยท Updated Nov 12, 2026 ยท NCT05224440

Long-Term Maintenance With Ketamine and Esketamine for Reduction of Suicide in High-Risk Patients With Depression

RecruitingPhase 4
Ages 18 to 70 ยท All sexes ยท Updated Nov 10, 2026 ยท NCT05450432

Natural History of Depression, Bipolar Disorder and Suicide Risk

RecruitingObservational study
Ages 18 to 120 ยท All sexes ยท Updated Nov 9, 2026 ยท NCT06462196

Preventing Suicidal Behavior With Diverse High-Risk Youth in Acute Care Settings

Recruiting
Ages 12 to 24 ยท All sexes ยท Updated Nov 4, 2026 ยท NCT06151158

Risk and Resilience to Suicide Following Late-Life Spousal Bereavement

Recruiting
Ages 60 and older ยท All sexes ยท Updated Oct 30, 2026 ยท NCT06191484

Developing a Recovery-Oriented Suicide Prevention Program for Young People at Clinical High Risk for Psychosis

Recruiting
Ages 12 to 30 ยท All sexes ยท Updated Oct 22, 2026 ยท NCT07756567

Army-SPRING Army-Suicide Prevention Research

RecruitingPhase 1Healthy volunteers welcome
All ages ยท All sexes ยท Updated Oct 19, 2026 ยท NCT06547008

Proximal Risk for Suicide in Adolescents

RecruitingObservational study
Ages 13 to 17 ยท All sexes ยท Updated Oct 16, 2026 ยท NCT06400810

Development of a Treatment Prognosis Calculator for the Prevention of Suicide

Recruiting
Ages 18 and older ยท All sexes ยท Updated Oct 16, 2026 ยท NCT06094218

Neurobiology of Suicide

RecruitingPhase 2Healthy volunteers welcome
Ages 18 to 70 ยท All sexes ยท Updated Oct 16, 2026 ยท NCT02543983

Alleviating Suicidality by Combining Psychotherapy and IM Ketamine for Rapid Treatment in the Emergency Department

RecruitingPhase 2
Ages 18 to 70 ยท All sexes ยท Updated Oct 15, 2026 ยท NCT07868913

Cortical rTMS as a Treatment for Depression

Recruiting
Ages 18 to 64 ยท All sexes ยท Updated Oct 13, 2026 ยท NCT05487911

Targeting Emotion Dysregulation to Reduce Suicide in People With Psychosis

Recruiting
Ages 18 and older ยท All sexes ยท Updated Oct 9, 2026 ยท NCT05440214

A Pilot Evaluation of a Digital Peer Support Intervention for Suicidal Adolescents

Recruiting
Ages 14 to 18 ยท All sexes ยท Updated Oct 5, 2026 ยท NCT06349915

Investigation of the Antidepressant Effects of (2R,6R)-HNK, an Enhancer of Synaptic Glutamate Release, in Treatment-Resistant Depression

RecruitingPhase 2
Ages 18 to 70 ยท All sexes ยท Updated Oct 5, 2026 ยท NCT06511908

NIMH Clinical Pathway in Rural Appalachian School-based Health Clinics

RecruitingHealthy volunteers welcome
Ages 12 to 17 ยท All sexes ยท Updated Oct 2, 2026 ยท NCT06808503

Plan and Protect: Safety Planning for Teens in Rural Emergency Departments

Recruiting
Ages 12 and older ยท All sexes ยท Updated Oct 2, 2026 ยท NCT07325474

Long-term Observation of Participants With Mood Disorders

RecruitingObservational studyHealthy volunteers welcome
Ages 18 to 99 ยท All sexes ยท Updated Oct 1, 2026 ยท NCT04877977

Efficacy of the I-CARE Digital Health Intervention

Recruiting
Ages 12 to 17 ยท All sexes ยท Updated Oct 1, 2026 ยท NCT07150832

Mind After Midnight

Recruiting
Ages 18 to 55 ยท All sexes ยท Updated Oct 1, 2026 ยท NCT07438912

Ketamine & Crisis Response Plan for Suicidal Ideation in the ED

RecruitingPhase 2/3
Ages 18 to 70 ยท All sexes ยท Updated Sep 30, 2026 ยท NCT05696691

WellPATH-PREVENT: A Mobile Intervention for Middle-Aged and Older Adults Hospitalized for Suicidal Ideation or Attempt

Recruiting
Ages 50 to 90 ยท All sexes ยท Updated Sep 23, 2026 ยท NCT05183230

Intensive Crisis Intervention

Recruiting
Ages 12 to 17 ยท All sexes ยท Updated Sep 21, 2026 ยท NCT06476886

Nudging Parental Actions for Youth Suicide Prevention

Recruiting
Ages 13 to 17 ยท All sexes ยท Updated Sep 18, 2026 ยท NCT07383714

From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.