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Hormonal Responses to a Mixed Meal in People With Cystic Fibrosis
RecruitingObservational studyHealthy volunteers welcome
Changes in Postprandial Hormone Levels in Cystic Fibrosis Related Diabetes.
Who can join
Ages 18 to 45 · All sexes · Healthy volunteers welcome
Full eligibility criteria
Inclusion Criteria: * Diagnosed with cystic fibrosis * Aged 18 to 45 years * Males and females of any race and ethnicity * Receiving highly effective CFTR modular therapy Exclusion Criteria: * Transplant recipient * Acute lung function decline or exacerbation within the last 3 months * Use of systemic glucocorticoids * Pregnancy * Known liver disease that would be expected to significantly impact metabolic variable as interpreted by a study doctor * The presence of any other disease or condition, as interpreted by any one of the study doctors, that would be expected to confound the responses to liquid mixed meal or make participation in the study dangerous to the individual * People who are cognitively impaired * People who do not speak English * For CFRD patients, a daily insulin requirement that exceeds 0.8 U/kg/day * Any prior history of diabetic ketoacidosis.
About the study
In this exploratory study, the hormonal responses to a mixed meal will be examined in people with cystic fibrosis. The aim of this study is to find correlates with impaired glucose tolerance that is associated with this population.
What is being tested
- Mixed meal (other)
Sponsor: University of Cincinnati · Participants: 61 · Started: Mar 28, 2023
Contact the study team
- Jason Winnick, PhD · Phone: 513-558-4437
- Shana Warner, PhD · Phone: 513-558-5545
Official record on ClinicalTrials.gov — NCT06163482
Locations in the U.S.
| Ohio | University of Cincinnati, Cincinnati |
Conditions
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.