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Individual Cerebral Hemodynamic Oxygenation Relationships (ICHOR 1)
Who can join
1 Minute – 18 Years · All sexes · Healthy volunteers welcome
Full eligibility criteria
Inclusion Criteria: * Individuals who are able to tolerate an MRI. * Are patients scheduled for a clinically indicated MRI. * Between birth and up to 18 years. Exclusion Criteria: * Presence of an MRI-incompatible device or implant (e.g. pacemakers, stents) * Unable to tolerate the enclosed spaces and loud noises for the duration of time in scanner required to obtain an MRI. * Preterm infants less than 25 weeks * Any patient who is clinically too unstable to extend their MRI by up-to 7.5 minutes.
About the study
This is an observational study in patients who require clinical anesthesia. The main purpose of this study is to understand whether there are differences in the cerebral blood flow, and oxygen metabolism affected by different types of anesthesia. Subjects who require clinical anesthesia for a clinical MRI and for whom the use of anesthetics for the exam are in clinical equipoise are asked to join the study. All eligible subjects will be asked to provide informed consent before participating in the study.
What is being tested
- MR Imaging (diagnostic test)
Sponsor: Children's Hospital Los Angeles · Participants: 1,000 · Started: Nov 1, 2018
Contact the study team
- Hannah E Wiseman, MPH · Phone: 323-361-3963
- Matthew T Borzage, PhD · Phone: 323-601-5757
Official record on ClinicalTrials.gov — NCT06195345
Locations in the U.S.
| California | Children's Hospital Los Angeles, Los Angeles |
Conditions
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.