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Traumatic Brain Injury clinical trials recruiting in the U.S.
138 studies for Traumatic Brain Injury are recruiting participants at sites across the United States.
Traumatic brain injury or TBI happens when a bump, blow, or other head injury causes damage to the brain. Treatment and outcome depend on how severe.
Cities with the most studies
- Boston, MA11 studies
- Minneapolis, MN11 studies
- Washington, DC8 studies
- Pittsburgh, PA7 studies
- Dallas, TX7 studies
- New York City, NY7 studies
- Cincinnati, OH6 studies
- Houston, TX6 studies
- Philadelphia, PA6 studies
- Seattle, WA5 studies
- San Diego, CA5 studies
- Baltimore, MD5 studies
- Gainesville, FL4 studies
- Newark, NJ4 studies
- Durham, NC4 studies
- San Francisco, CA4 studies
- St. Louis, MO4 studies
- Cedar Rapids, IA4 studies
- Portland, OR4 studies
- Columbus, OH4 studies
- Chicago, IL4 studies
- San Antonio, TX3 studies
- Clifton, NJ3 studies
- Sacramento, CA3 studies
- Albuquerque, NM3 studies
- Bridgeport, CT3 studies
- Miami, FL3 studies
- Los Angeles, CA3 studies
- Lexington, KY3 studies
By state
- California17 studies
- Colorado4 studies
- District of Columbia3 studies
- Florida12 studies
- Illinois5 studies
- Iowa4 studies
- Kentucky4 studies
- Maryland10 studies
- Massachusetts12 studies
- Michigan4 studies
- Minnesota11 studies
- Missouri4 studies
- New Jersey8 studies
- New Mexico3 studies
- New York11 studies
- North Carolina10 studies
- Ohio13 studies
- Oregon5 studies
- Pennsylvania13 studies
- Texas16 studies
- Virginia3 studies
- Washington6 studies
- Wisconsin4 studies
Recently updated studies
Depth Electrode Cortical Reverberation Monitoring After Traumatic Brain Injury
Recruiting
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07842458Comparison of Two Group Wellness Interventions for Individuals With Neurologic Conditions and Their Support Persons
Recruiting
Ages 18 and older · All sexes · Updated Sep 21, 2026 · NCT05048966A Study to Develop a Blood-based Test for Aiding the Diagnosis/Prognosis of Traumatic Brain Injury in Adults and for Monitoring the Development of Secondary Events in Patients Diagnosed With Traumatic Brain Injury
RecruitingObservational study
Ages 18 and older · All sexes · Updated Sep 21, 2026 · NCT07455136Long-term Brain Stimulation of the Motor Ventral Thalamus (VOP/VIM) to Improve Motor Function
RecruitingHealthy volunteers welcome
Ages 18 to 80 · All sexes · Updated Sep 18, 2026 · NCT07056348Stimulating Specific Brain Areas (VOP/VIM) With Electricity to Improve Movement and Muscle Control
Recruiting
Ages 18 to 75 · All sexes · Updated Sep 18, 2026 · NCT07056361Pilot Study of BCAA on Sleep
Recruiting
Ages 18 to 89 · All sexes · Updated Sep 17, 2026 · NCT03990909Examining the Efficacy of the Man Therapy Platform in Reducing Problematic Anger Among Military Service Members With and Without a TBI History
Recruiting
Ages 18 and older · Men · Updated Sep 16, 2026 · NCT07604701Home-based Vision Rehabilitation Guided by Brain Imaging
Recruiting
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT07635329Vision Improvement Through Behavioral Rehabilitation And Neuroplasticity Training
Recruiting
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT07105358Low-Tech Treatments for Obstructive Sleep Apnea
RecruitingPhase 1/2
Ages 18 to 65 · All sexes · Updated Sep 10, 2026 · NCT07301710The EBC Recovery Study
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT04712591Objectively Diagnose and Monitor Treatment of Light Sensitivity
RecruitingHealthy volunteers welcome
Ages 18 to 80 · All sexes · Updated Sep 8, 2026 · NCT03694626CoMind Early Feasibility Study
RecruitingObservational study
Ages 18 and older · All sexes · Updated Sep 4, 2026 · NCT06368648Mobile Health Self-Management and Support System for Chronic and Complex Health Conditions
RecruitingHealthy volunteers welcome
Ages 12 and older · All sexes · Updated Sep 3, 2026 · NCT02592291Non-Trauma Intervention to Treat PTSD for Veterans and Service Members Suffering From a TBI
Recruiting
Ages 18 and older · All sexes · Updated Aug 28, 2026 · NCT07351305Brain Blood Flow and Cerebral Autoregulation Monitoring in Critically Ill Children
RecruitingObservational study
1 Day – 17 Years · All sexes · Updated Aug 27, 2026 · NCT07613918Saline Versus Balanced Crystalloid in Traumatic Brain Injury
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Aug 26, 2026 · NCT06953674Cranial Ultrasound for Point of Care Intracranial Pathology Detection in Pediatrics
RecruitingObservational study
Up to age 18 · All sexes · Updated Aug 24, 2026 · NCT06697808Control Network Neuromodulation to Enhance Cognitive Training in Complex Traumatic Brain Injury
Recruiting
Ages 18 to 59 · All sexes · Updated Aug 21, 2026 · NCT05236010Feasibility of SUPPORT-TBI
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Aug 19, 2026 · NCT07625098Methylphenidate for the Treatment of PTSD With Associated Neurocognitive Complaints
RecruitingPhase 4
Ages 18 to 65 · All sexes · Updated Aug 19, 2026 · NCT05776056ENGAGE-TBI Feasibility Study
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Aug 18, 2026 · NCT07549997Electrical Stimulation Exercise for Individuals With Lower Limb Paralysis
Recruiting
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT07768761Understanding and Treating Traumatic Brain Injury (TBI) Associated Photophobia With Botulinum Toxin Type A (BoNT-A)
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Aug 14, 2026 · NCT06293300Evaluation of the SCALED (SCaling AcceptabLE cDs)
RecruitingObservational study
Ages 18 and older · All sexes · Updated Aug 12, 2026 · NCT05628207From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.