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Traumatic Brain Injury clinical trials recruiting in the U.S.

138 studies for Traumatic Brain Injury are recruiting participants at sites across the United States.

Traumatic brain injury or TBI happens when a bump, blow, or other head injury causes damage to the brain. Treatment and outcome depend on how severe.

Cities with the most studies

By state

Recently updated studies

Depth Electrode Cortical Reverberation Monitoring After Traumatic Brain Injury

Recruiting
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07842458

Comparison of Two Group Wellness Interventions for Individuals With Neurologic Conditions and Their Support Persons

Recruiting
Ages 18 and older · All sexes · Updated Sep 21, 2026 · NCT05048966

Long-term Brain Stimulation of the Motor Ventral Thalamus (VOP/VIM) to Improve Motor Function

RecruitingHealthy volunteers welcome
Ages 18 to 80 · All sexes · Updated Sep 18, 2026 · NCT07056348

Stimulating Specific Brain Areas (VOP/VIM) With Electricity to Improve Movement and Muscle Control

Recruiting
Ages 18 to 75 · All sexes · Updated Sep 18, 2026 · NCT07056361

Pilot Study of BCAA on Sleep

Recruiting
Ages 18 to 89 · All sexes · Updated Sep 17, 2026 · NCT03990909

Home-based Vision Rehabilitation Guided by Brain Imaging

Recruiting
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT07635329

Vision Improvement Through Behavioral Rehabilitation And Neuroplasticity Training

Recruiting
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT07105358

Low-Tech Treatments for Obstructive Sleep Apnea

RecruitingPhase 1/2
Ages 18 to 65 · All sexes · Updated Sep 10, 2026 · NCT07301710

The EBC Recovery Study

RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT04712591

Objectively Diagnose and Monitor Treatment of Light Sensitivity

RecruitingHealthy volunteers welcome
Ages 18 to 80 · All sexes · Updated Sep 8, 2026 · NCT03694626

CoMind Early Feasibility Study

RecruitingObservational study
Ages 18 and older · All sexes · Updated Sep 4, 2026 · NCT06368648

Mobile Health Self-Management and Support System for Chronic and Complex Health Conditions

RecruitingHealthy volunteers welcome
Ages 12 and older · All sexes · Updated Sep 3, 2026 · NCT02592291

Non-Trauma Intervention to Treat PTSD for Veterans and Service Members Suffering From a TBI

Recruiting
Ages 18 and older · All sexes · Updated Aug 28, 2026 · NCT07351305

Brain Blood Flow and Cerebral Autoregulation Monitoring in Critically Ill Children

RecruitingObservational study
1 Day – 17 Years · All sexes · Updated Aug 27, 2026 · NCT07613918

Saline Versus Balanced Crystalloid in Traumatic Brain Injury

RecruitingPhase 3
Ages 18 and older · All sexes · Updated Aug 26, 2026 · NCT06953674

Cranial Ultrasound for Point of Care Intracranial Pathology Detection in Pediatrics

RecruitingObservational study
Up to age 18 · All sexes · Updated Aug 24, 2026 · NCT06697808

Control Network Neuromodulation to Enhance Cognitive Training in Complex Traumatic Brain Injury

Recruiting
Ages 18 to 59 · All sexes · Updated Aug 21, 2026 · NCT05236010

Feasibility of SUPPORT-TBI

RecruitingPhase 1
Ages 18 and older · All sexes · Updated Aug 19, 2026 · NCT07625098

Methylphenidate for the Treatment of PTSD With Associated Neurocognitive Complaints

RecruitingPhase 4
Ages 18 to 65 · All sexes · Updated Aug 19, 2026 · NCT05776056

ENGAGE-TBI Feasibility Study

RecruitingPhase 1
Ages 18 and older · All sexes · Updated Aug 18, 2026 · NCT07549997

Electrical Stimulation Exercise for Individuals With Lower Limb Paralysis

Recruiting
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT07768761

Understanding and Treating Traumatic Brain Injury (TBI) Associated Photophobia With Botulinum Toxin Type A (BoNT-A)

RecruitingPhase 2
Ages 18 and older · All sexes · Updated Aug 14, 2026 · NCT06293300

Evaluation of the SCALED (SCaling AcceptabLE cDs)

RecruitingObservational study
Ages 18 and older · All sexes · Updated Aug 12, 2026 · NCT05628207

From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.