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Menthol, Inflammation, and Nicotine Transition Study

Effect of Menthol to Non-Menthol Cigarette Switching on Subclinical Inflammatory Biomarkers of Cardiovascular Health: Simulating a Menthol Cigarette Ban

Who can join

Ages 21 to 85 · All sexes · Healthy volunteers welcome

Inclusion criteria

* Men and women between 21-85 years old
* Currently uses menthol cigarettes
* Daily smoking rate of ≥5 cigarettes/day for ≥1 year
* Currently own and regularly use an iOS/Android smartphone device able to download the LifeData application
* Able to read and communicate fluently in English

Exclusion criteria

* Currently pregnant or breastfeeding
* Actively trying to quit smoking
* Current heavy alcohol use
* Frequent use of non-menthol cigarettes, other smoking products, or illicit substances
* History of severe medical/psychiatric condition or treatment

About the study

This study will focus on examining the potential impact of menthol flavoring in cigarettes on biomarkers of systemic inflammation as a subclinical indicator of cardiovascular disease risk.

What is being tested

• Cigarette Type Switching (other)

Sponsor: Rosalind Franklin University of Medicine and Science · Participants: 68 · Started: Mar 26, 2024

Contact the study team

• Nancy C Jao, PhD · Phone: 847-578-8747

Official record on ClinicalTrials.gov — NCT06232447

Locations in the U.S.

Conditions

• Smoking

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.