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Behavioral Exercise Training to Reduce Cardiovascular Disease Risk
RecruitingPhase 1/2
Behavioral Exercise Training to Reduce Cardiovascular Disease Risk in Men Undergoing Androgen Deprivation Therapy (EXTRA-PC)
Who can join
Ages 40 to 85 · Men
Full eligibility criteria
Inclusion Criteria: * Be diagnosed with stage II/III/IV prostate cancer * Be currently undergoing treatment with ADT (intermittent or prolonged) * Have completed local curative-intent treatment, including prostatectomy or definitive radiation; * Be \>40 years of age up to 85; * Be willing to sign an informed consent with HIPAA authorization form; * Not have any hearing or sight impairments that result in the inability to use the telephone or hear normal conversation; * Must be able to join an intervention group by personal computer, smartphone or telephone call and should agree to recording of an interview; * Be without any serious medical condition that precludes safe participation in an exercise program; * Speak English Exclusion Criteria: * Be unable to undergo MRI (i.e., ferromagnetic materials in body, inability to lie flat, claustrophobia); * Have contraindications to exercise testing; * Have pre-existing overt cardiovascular disease/heart failure; * Active illness/infection; * Hemoglobin \< 7.0 grams/dL * Platelet count \< 10 x 109/L
About the study
To test the preliminary effectiveness of a home-based exercise training (ET) intervention to improve exercise capacity (VO2 peak \& 6-minute walk distance \[6MWD\]) among prostate cancer (PC) patients compared to controls receiving healthy living education (HLE) at 12 weeks.
What is being tested
- Exercise Training Intervention (behavioral)
- Healthy Living Education (behavioral)
Sponsor: Virginia Commonwealth University · Participants: 60 · Started: Feb 21, 2024
Contact the study team
- Alexander R Lucas, PhD · Phone: 804 628-6610
- Alexandra Marshall, MS · Phone: 804 628-1215
Official record on ClinicalTrials.gov — NCT06237179
Locations in the U.S.
| Virginia | Richmond Veterans Affairs Medical Center, Richmond (Not yet recruiting) Virginia Commonwealth University Massey Cancer Center, Richmond |
Conditions
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.