Home › Drug Use and Addiction › NCT06307977

Couples Motivational Interviewing to Reduce Drug Use and HIV Risk in Vulnerable Male Couples

Who can join

Ages 18 to 55 · Men · Healthy volunteers welcome

Inclusion Criteria:

* Have a main partner who is another cisgender male and have been in a relationship for 3 month or longer
* Index participant must be between 18 and 55; Main partner can be any age 18 and older
* One participant must be HIV negative (as confirmed by rapid test)
* One participant must have used at least 1 drug in the past 30 days (cocaine/crack, opiates, misuse of prescription medication, stimulants, psychedelics, ecstasy, ketamine, GHB, amyl nitrite)
* Index participant must have engaged in TRB in the past 30 days- Defined as CAS with a casual partner, or a serodiscordant or non-monogamous main partner
* Live in the United States
* Speak and read English

Exclusion Criteria

* Any signs of serious mental illness or cognitive deficit
* Current suicidal/homicidal ideations
* History of IPV with their main partner and safety concerns in the current relationship.

About the study

This study utilizes a randomized controlled trial design to evaluate the efficacy of couples motivational interviewing (MI) to reduce the frequency and severity of illicit drug use and frequency of HIV transmission risk behavior (TRB). Participants are randomized to one of two conditions: couples MI or standard couples HIV testing and counseling (CHTC).

What is being tested

• Couples Health Project (behavioral)

Sponsor: Hunter College of City University of New York · Participants: 360 · Started: May 25, 2024

Contact the study team

• Tyrel J Starks, PHD · Phone: 212-206-7919
• Demetria Cain, PHD · Phone: 212-206-7919

Official record on ClinicalTrials.gov — NCT06307977

Locations in the U.S.

Conditions

• Drug Use and Addiction
• HIV

From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.