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Optimization of Postoperative Bowel Habits

Optimization of Postoperative Bowel Habits Following Pelvic Reconstructive Surgery: a Randomized Controlled Trial

Who can join

Ages 18 and older · Women

Inclusion Criteria:

* Women ages 18 and older scheduled to undergo vaginal pelvic organ prolapse repair

Exclusion Criteria:

* Women younger than 18 years old
* Those unable to provide consent
* Preexisting chronic laxative use
* Conditions that could affect bowel function including, inflammatory bowel disease, irritable bowel syndrome, colorectal cancer, rectovaginal fistula; concurrent bowel surgery; intraoperative bowel injury

About the study

Project is a trial, in which women undergoing vaginal surgery for pelvic organ prolapse will be randomized 1:1 to a postoperative bowel regimen of either oral senna or rectal bisacodyl suppository.

What is being tested

• Senna Tab (dietary supplement)
• Dulcolax Suppositories (dietary supplement)

Sponsor: Wake Forest University Health Sciences · Participants: 88 · Started: Oct 16, 2024

Contact the study team

• Christina M Mezes, MD · Phone: 336-713-4098
• Sachin N Vyas, MS, PhD · Phone: 336-713-4098

Official record on ClinicalTrials.gov — NCT06335797

Locations in the U.S.

Conditions

• Constipation

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.