Home › Mild Cognitive Impairment
Mild Cognitive Impairment clinical trials recruiting in the U.S.
237 studies for Mild Cognitive Impairment are recruiting participants at sites across the United States.
In mild cognitive impairment (MCI), you have more memory and thinking problems than others your age, but they don't interfere with your everyday life.
Cities with the most studies
- New York City, NY24 studies
- Boston, MA23 studies
- Chicago, IL16 studies
- Baltimore, MD14 studies
- Los Angeles, CA12 studies
- Miami, FL12 studies
- San Francisco, CA11 studies
- Atlanta, GA10 studies
- Houston, TX10 studies
- Birmingham, AL10 studies
- Philadelphia, PA10 studies
- Durham, NC9 studies
- Phoenix, AZ9 studies
- Indianapolis, IN8 studies
- Washington, DC8 studies
- Tampa, FL8 studies
- Gainesville, FL8 studies
- Portland, OR8 studies
- St. Louis, MO8 studies
- Dallas, TX7 studies
- Columbus, OH7 studies
- Farmington Hills, MI6 studies
- Orlando, FL6 studies
- Irvine, CA6 studies
- Hollywood, FL6 studies
- Providence, RI6 studies
- Seattle, WA6 studies
- San Diego, CA6 studies
- San Antonio, TX6 studies
- Pittsburgh, PA6 studies
- Charleston, SC6 studies
- The Villages, FL5 studies
- Boulder, CO5 studies
- The Bronx, NY5 studies
- New Haven, CT5 studies
- Ann Arbor, MI5 studies
- Mountain View, CA5 studies
- West Palm Beach, FL5 studies
- Winston-Salem, NC5 studies
- Jacksonville, FL5 studies
By state
- Alabama10 studies
- Arizona14 studies
- California41 studies
- Colorado13 studies
- Connecticut9 studies
- District of Columbia4 studies
- Florida27 studies
- Georgia13 studies
- Illinois20 studies
- Indiana11 studies
- Iowa3 studies
- Kentucky3 studies
- Maryland20 studies
- Massachusetts29 studies
- Michigan11 studies
- Minnesota6 studies
- Mississippi3 studies
- Missouri10 studies
- New Hampshire4 studies
- New Jersey8 studies
- New York32 studies
- North Carolina15 studies
- Ohio11 studies
- Oregon10 studies
- Pennsylvania13 studies
- Rhode Island6 studies
- South Carolina8 studies
- Tennessee9 studies
- Texas24 studies
- Utah5 studies
- Virginia5 studies
- Washington7 studies
Recently updated studies
PET Imaging of Phosphodiesterase-4 (PDE4) in Volunteers With Alzheimer Disease (AD) or Mild Cognitive Impairment (MCI)
RecruitingPhase 1Healthy volunteers welcome
Ages 50 to 100 · All sexes · Updated Nov 13, 2026 · NCT07169630Computerized Tests of Cognitive Decline in Presymptomatic Alzheimer's Disease
RecruitingHealthy volunteers welcome
Ages 18 to 89 · All sexes · Updated Nov 13, 2026 · NCT04800588Adaptango Performance PRocess for Older Adults Community reHabilitation
RecruitingHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Nov 13, 2026 · NCT07824128Remotely Supervised tDCS+ for Complex Attention in mTBI (Cognetric)
Recruiting
Ages 18 to 60 · All sexes · Updated Nov 13, 2026 · NCT06413173Designing a Spatial Navigation Intervention Protocol Informed by Region-specific Brain Activation for Mild Cognitive Impairment
RecruitingHealthy volunteers welcome
Ages 65 and older · All sexes · Updated Nov 12, 2026 · NCT07225400Prediction and Prevention of Postoperative Mortality and Morbidity
Recruiting
Ages 65 and older · All sexes · Updated Nov 12, 2026 · NCT06042413Tennessee Alzheimer's Project
RecruitingObservational studyHealthy volunteers welcome
Ages 60 and older · All sexes · Updated Nov 10, 2026 · NCT05372172CMN LIFU for Enhanced Amyloid Reduction (CLEART Study)
Recruiting
Ages 65 and older · All sexes · Updated Nov 9, 2026 · NCT07866768HEARS-NPS: Addressing Hearing Loss as a Common Unmet Contributor of Neuropsychiatric Symptoms
RecruitingHealthy volunteers welcome
Ages 60 to 100 · All sexes · Updated Nov 6, 2026 · NCT06930560Flutemetamol F 18 Injection Formulation Comparison
RecruitingPhase 2
Ages 50 to 110 · All sexes · Updated Nov 5, 2026 · NCT07873463Feasibility of A Smartphone Application Intervention in Community Settings: A Pretest-Posttest Pilot Study
RecruitingHealthy volunteers welcome
Ages 50 to 100 · All sexes · Updated Nov 5, 2026 · NCT07313540Neurobehavioral Changes Following Spaceflight Stressors
RecruitingHealthy volunteers welcome
Ages 21 to 60 · All sexes · Updated Nov 5, 2026 · NCT07293494Treating Insomnia in Mild Cognitive Impairment
Recruiting
Ages 60 and older · All sexes · Updated Nov 5, 2026 · NCT06687161Telehealth-Adapted Compensatory Training and Intervention for Cognition
Recruiting
Ages 65 to 84 · All sexes · Updated Nov 5, 2026 · NCT07366346A Study of LY3439539 in Participants With Alzheimer's Disease
RecruitingPhase 1
Ages 50 to 85 · All sexes · Updated Nov 4, 2026 · NCT07598370A Study of Donanemab (LY3002813) in Participants With Early Cognitive Decline (TRAILBLAZER-ALZ 7)
RecruitingPhase 2
Ages 55 to 85 · All sexes · Updated Nov 4, 2026 · NCT07589595Rural Veteran and Care Partner Walking Program
RecruitingHealthy volunteers welcome
Ages 19 to 90 · All sexes · Updated Nov 3, 2026 · NCT07914218HOBSCOTCH-MS-Efficacy Trial
Recruiting
Ages 20 to 75 · All sexes · Updated Nov 2, 2026 · NCT06951919PET Imaging of Cyclooxygenases in Neurodegenerative Brain Disease
RecruitingPhase 1Healthy volunteers welcome
Ages 18 to 99 · All sexes · Updated Nov 2, 2026 · NCT04396873HOBSCOTCH-YOUTH and Young Adults
Recruiting
Ages 13 to 29 · All sexes · Updated Nov 2, 2026 · NCT07735715A First-In-Human Study of LY3954068 in Participants With Early Symptomatic Alzheimer's Disease
RecruitingPhase 1
Ages 50 to 85 · All sexes · Updated Oct 29, 2026 · NCT06297590ME/CFS Brain Fog: Cognitive Rehabilitation Trial
Recruiting
Ages 18 and older · All sexes · Updated Oct 29, 2026 · NCT07523113Cognitive Dysfunction and Inflammation in Depression: Experimental Inhibition Via Infliximab
RecruitingPhase 2
Ages 25 to 50 · All sexes · Updated Oct 27, 2026 · NCT06136546A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's Disease
RecruitingPhase 3
Ages 60 to 85 · All sexes · Updated Oct 27, 2026 · NCT06976216Combating Alzheimer's Through Sleep and Exercise
RecruitingHealthy volunteers welcome
Ages 55 to 80 · All sexes · Updated Oct 27, 2026 · NCT04855630From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.