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Low and High Flow Suctioning in Intubated Infants
Physiological Consequences of Low and High Flow Endotracheal Suctioning Devices in Intubated Preterm and Term Infants
Who can join
28 Days · All sexes
Full eligibility criteria
Inclusion Criteria: * Preterm and term infants with birth weight more than 1000g receiving ETT suctioning Exclusion Criteria: * Infants with cyanotic congenital heart disease and cardiac rhythm disorders (arrythmias) will be excluded from the study.
About the study
Preterm and term intubuted infants in the NICU will undergo two sequential suctioning procedures: a new, FDA-approved suction device called EXSALTA (ED) and the standard conventional wall (SCW). The physiological consequences, i.e. changes in heart rate (HR), oxygen saturation (SpO2), cerebral oxygenation (C-rSO2), and cerebral fractional oxygen extraction (C-FOE) between ED and SCW ETT tracheal suctioning system in both open and closed catheter system settings will be evaluated using a randomized cross over design in preterm and term infants receiving mechanical ventilation via an ETT. This study will evaluate the hypothesis that there will be significantly lower variations in HR, SpO2, C-rSO2, and C-FOE during ETT suctioning with ED compared to SCW suctioning systems under both open and close ETT suction settings.
What is being tested
- Exsalta Suction Device (device)
Sponsor: Columbia University · Participants: 30 · Started: Sep 4, 2024
Contact the study team
- Rakesh Sahni, MD · Phone: 212-305-9743
Official record on ClinicalTrials.gov — NCT06443970
Locations in the U.S.
| New York | Columbia University Irving Medical Center, New York |
Conditions
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.