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Multimodal Investigation of Neural Plasticity

Multimodal Investigation of Neural Plasticity Induced by Non-invasive Brain Stimulation

Who can join

Ages 60 and older · All sexes · Healthy volunteers welcome

Inclusion Criteria:

* Normal cognition for HC and diagnosis of Mild Cognitive Impairment (MCI) for MCI participants
* Right-handedness
* Magnetic resonance compatible, criteria that also apply for high definition transcranial direct current stimulation (HD-tDCS; e.g., absence of metallic or electronic implants in the upper body or head)

Exclusion Criteria:

* History of other contributing neurological or medical conditions known to affect cognitive functioning
* Significant mental illness
* Sensory impairments that limit ability to participate
* History of alcohol or drug abuse/dependence

About the study

This study will evaluate the effects of a form of non-invasive brain stimulation on brain functioning and memory in cognitively intact older adults (healthy controls, HC) and in those with mild cognitive impairment (MCI).

What is being tested

• sham tDCS (device)
• active tDCS (device)

Sponsor: University of Michigan · Participants: 80 · Started: May 13, 2024

Contact the study team

• Harini Babu, MSc · Phone: 734-647-3704
• Eileen Robinson, RN-BC · Phone: 734-763-1356

Official record on ClinicalTrials.gov — NCT06453980

Locations in the U.S.

Conditions

• Mild Cognitive Impairment

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.