Low-Dose Ketamine Infusion During Burn Wound Care
A Randomized, Placebo-Controlled, Double-Blind Evaluation of Low-Dose Ketamine Infusion During Burn Wound Care Procedures to Improve Pain Intensity and Reduce Opioid Consumption
Who can join
Ages 18 and older · All sexes
Full eligibility criteria
Inclusion Criteria: * Admitted to burn service with thermal injury Exclusion Criteria: * unable/unwilling to consent within 72 hours * unable to report NRS * known contraindication to ketamine * \< than 18 years of age * pregnant * incarcerated * TBSA over 50 %
About the study
The current standard of care (SOC) (i.e. fentanyl and midazolam) offers limited efficacy for preventing or relieving pain. Ketamine infusions may provide the benefits of analgesia, minimize adverse events, and reduce opioid use. The purpose of this study is to determine if adding a low dose ketamine infusion during wound care will safely provide pain relief for patients with burn injury.
What is being tested
- Ketamine (drug)
- 0.9% NaCl (drug)
Sponsor: University of Tennessee · Participants: 140 · Started: Jul 8, 2024
Contact the study team
- David M Hill, Pharm.D. · Phone: 1-901-545-7100
Official record on ClinicalTrials.gov — NCT06506565
Locations in the U.S.
| Tennessee | Regional One Health, Memphis |
Conditions
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.