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Helmsley 3.0: Abbreviated MRE

Comparison of Conventional Clinical and Abbreviated MR Enterography Protocols in Children and Adults With Crohn's Disease

Who can join

Ages 10 and older · All sexes

Inclusion Criteria:

* Established Crohn's disease diagnosis in patients 10 and older
* Undergoing clinical magnetic resonance enterography (MRE) examinations for any reason(s) below

  * Staging/ restaging/ follow- up of intestinal inflammation
  * Evaluation of known or suspected luminal narrowing/ stricturing disease
  * Evaluation of known or suspected internal penetrating disease

Exclusion Criteria:

* Undergoing initial imaging for suspected Crohn's disease where the diagnosis of Crohn's disease has yet to be definitively established
* New Crohn's disease diagnosis, undergoing baseline imaging
* Isolated colonic disease
* Known or suspected pregnancy
* Contraindication to magnetic resonance imaging (MRI)
* Ileostomy or prior ileal resection
* Less than 10 years of age
* Unable or unwilling to follow imaging procedures
* Non- English speaking

About the study

The purpose of our study is to compare an abbreviated magnetic resonance imaging (MRI) of the bowel or magnetic resonance enterography (MRE) protocol to a conventional, standard of care MRE in children and adults with Crohn's Disease.

What is being tested

• Magnetic Resonance Imaging (MRI) or Magnetic Resonance Enterography (MRE) (diagnostic test)

Sponsor: Children's Hospital Medical Center, Cincinnati · Participants: 300 · Started: Sep 1, 2024

Contact the study team

• Tanita Dean · Phone: (513) 803-0853
• Kristi Cole · Phone: (513)636-9403

Official record on ClinicalTrials.gov — NCT06533228

Locations in the U.S.

Conditions

• Crohn's Disease

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.