The Influence of Sleep on Cardiovascular Outcomes

Inclusion Criteria:

* Ostensibly healthy men and women Subgroup study (chronic pain)
* Satisfies diagnostic criteria for fibromyalgia according to the Widespread Pain Index - Symptom Severity (WPI-SS) scale with the following three conditions being met:

  1. Widespread pain index (WPI) ≥7 and symptom severity (SS) scale score ≥5 or WPI 3-6 and SS scale score ≥9.
  2. Symptoms have been present at a similar level for at least 3 months.
  3. The patient does not have a disorder that would otherwise explain the pain.

Exclusion Criteria:

* No history of drug or alcohol dependency.
* Must be current non-smokers, and are required to have a history of less than 5 pack years of smoking.
* No history of working irregular day and night hours, regular night work, or rotating shift work for the 1 year prior to the study. In addition to this, individuals must not have traveled across more than 1 time zone during the 3 months prior to the study.
* Chronobiologic and sleep disorders.
* Diseases of the cardiovascular system.
* Hypertension. Individuals will be allowed to be normotensive (resting systolic blood pressure of \<140/90 mmHg, measured on more than one occasion) or uncomplicated stage 1 hypertension (systolic BP between 140 and 159 mmHg or a diastolic BP between 90 and 99 mmHg).
* Disorders of the respiratory system.
* Pre-diabetes/Diabetes. For participants who have self-reported pre-diabetes/diabetes.
* Disorders of the kidney and urinary tract.
* Infectious diseases.
* Disorders of the gastrointestinal system.
* Disorders of the immune system.
* Disorders of the hematopoietic system.
* Neoplastic diseases.
* Endocrine and metabolic diseases.
* Neurologic disorders.
* Must not be participating in another research study that would influence their safe participation in the study.