Physiologic Effects of Nasal High Flow on Exercise Tolerance in COPD
Recruiting
Physiologic Effects of Nasal High Flow on Exercise Tolerance in Chronic Obstructive Pulmonary Disease (COPD)
Who can join
Ages 18 to 100 · All sexes
Full eligibility criteria
Inclusion Criteria: * Able to consent * Age 18 years or older * Diagnosis of COPD * Ability to ambulate without assistance * Use of low-flow nasal cannula ≤ 4 L/min or no supplemental oxygen (O2) at all Exclusion Criteria: * Pregnancy * Being on bedrest * Inability to consent or cooperate with the study * Using of \> 4 L/min of supplemental O2 or requiring non-invasive ventilation during the daytime * Hemodynamic instability (resting heart rate \> 130/minute, systolic blood pressure of ≤ 90 mmHg or ≥ 180 mmHg) * Metal implants in the thoracic regions (pacemakers, Automatic Implantable Cardioverter Defibrillator (AICD), plates, screws, rods, and disc replacements)
About the study
This study aims to assess whether to describe the effects of the administration of nasal high flow (NHF) at 70 liters per minute (L/min) in a 6-Minute Walk Test (6-MWT) among Chronic Obstructive Pulmonary Disease (COPD) patients and to characterize the association between self-reported dyspnea with and without NHF at 70 L/min following a 6-MWT.
What is being tested
- Nasal High Flow Cannula (device)
- Nasal Low Flow Cannula (device)
Sponsor: University of Miami · Participants: 45 · Started: Dec 12, 2024
Contact the study team
- Saramaria Afanador Castiblanco, M.D. · Phone: 305-243-2568
Official record on ClinicalTrials.gov — NCT06578156
Locations in the U.S.
| Florida | University of Miami, Miami |
Conditions
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.