Home › Post-Traumatic Stress Disorder › NCT06670079
Prolonged Exposure Therapy to Treat Posttraumatic Stress Disorder in Pregnant Patients
Who can join
Ages 18 and older · Women
Full eligibility criteria
Inclusion Criteria: * Female * \>18 years old * Gestational age ≤ 25 weeks * Meet current DSM-5 posttraumatic stress disorder criteria based on the Clinician Administered PTSD Scale for DSM-5 * Participants receiving psychotropic medications must be maintained on a stable dose for \>14 days prior to enrollment. Exclusion Criteria: * Male * Under 18 years old * Gestational age \> 25 weeks * No current diagnosis of PTSD * Current delusions or hallucinations, unstable bipolar disorder, imminent risk for suicide as assessed by the Mini International Neuropsychiatric Interview * Enrolled in another ongoing evidence-based treatment for PTSD.
About the study
The goal of this clinical trial is to learn if a treatment for adults with PTSD called prolonged exposure + incentives (PE+) works to treat pregnant patients. The main question it aims to answer is:
Does PE+ decrease PTSD symptoms?
All participants will receive PE+ to see if their PTSD symptoms at the end of the trial are less than at the beginning.
Participants will:
* Receive individual PE+ therapy for 1 hour weekly for 12 weeks. * Receive financial incentives for attending each PE+ session. * Attend assessment visits every 4 weeks for the 12 weeks of the trial. * Allow research staff to collect some information about their labor and delivery from their medical records after their babies are born.
What is being tested
- Prolonged exposure therapy + incentives for therapy session attendance (behavioral)
Sponsor: University of Vermont · Participants: 30 · Started: Feb 5, 2026
Contact the study team
- Kelly Peck, PhD · Phone: 802-656-9610
Official record on ClinicalTrials.gov — NCT06670079
Locations in the U.S.
| Vermont | University of Vermont, Burlington |
Conditions
From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.