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Comparison of Healing Measures Tibial Fractures Following Standard Intramedullary Nailing or Micromotion Tibial Intramedullary Nailing

Comparison of Healing Measures in Diaphyseal Tibial Fractures Following Standard Intramedullary Nailing or Micromotion Tibial Intramedullary Nailing

Who can join

Ages 18 to 85 · All sexes

Inclusion Criteria:

* Age 18 - 85 years
* Stable Tibial fracture recommended for surgical intervention

Exclusion Criteria:

* Patients not meeting inclusion criteria
* Unstable fracture patterns e.g. those needing a secondary intervention - masquelet/cement spacer)
* Previously non-ambulatory patients
* Delayed presentation of fracture (\>4 weeks)
* Fractures that the treating surgeon indicates requires additional fixation strategies to achieve stability
* Patients with an achieve infection or wound at the surgical site
* Any previous ligament or fracture surgery on the index site
* Inflammatory rheumatic disease or other rheumatic disease-
* Immune compromised patients (hepatitis, HIV, etc.)
* Unwilling or unable to participate or follow study protocol

About the study

The primary purpose of this study is to perform a high-quality randomized control trial comparing intramedullary tibial nail fixation with standard design nails to a micromotion tibial nail device, to evaluate the rates of union and post-operative outcomes.

What is being tested

• micromotion intramedullary nail cohort (procedure)
• standard intramedullary nail cohort (procedure)

Sponsor: University of Alabama at Birmingham · Participants: 100 · Started: Apr 30, 2025

Contact the study team

• Joseph Johnson, MD · Phone: 205-934-1041

Official record on ClinicalTrials.gov — NCT06679049

Locations in the U.S.

Conditions

• Leg Injuries and Disorders

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.