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Cranial Ultrasound for Point of Care Intracranial Pathology Detection in Pediatrics

Cranial Ultrasound for Point of Care Intracranial Pathology Detection in Pediatrics (CUPID-Peds)

Who can join

Up to age 18 · All sexes

Inclusion Criteria:

* Patients requiring a head computed tomography (CT) or brain MRI as the standard of care
* Seen in the pediatric Emergency Department or Pediatric Intensive Care Unit at Atrium Health Wake Forest Brenner Children's Hospital or Levine Children's Hospital

Exclusion Criteria:

* Patients with open skull fractures
* Previous hemicraniectomy
* Existing surgical defect in the skull
* Patients being transitioned to comfort care

About the study

To improve patient selection for head CT, a safe and high sensitivity screening neuroimaging modality is needed. Currently many clinicians must make treatment decisions based solely on the patients clinical exam, which has low sensitivity and specificity and low inter-rater reliability. This study is being done to learn more about B-mode cranial point-of-care ultrasound (cPOCUS). Ultrasound has several advantages. It is a safe, non- invasive, low-cost, fast and portable bedside tool without ionizing radiation exposure.

Sponsor: Wake Forest University Health Sciences · Participants: 169 · Started: Nov 24, 2024

Contact the study team

• Denise Fraga, MD · Phone: 704-355-3181

Official record on ClinicalTrials.gov — NCT06697808

Locations in the U.S.

Conditions

• Traumatic Brain Injury
• Head Injuries

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.