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Post-Stroke Sensory Reweighting on Walking and Balance Outcomes

Tracking the Development and Influence of Post-Stroke Sensory Reweighting on Walking and Balance Outcomes

Who can join

Ages 18 and older · All sexes

Inclusion Criteria:

1. First ever clinical stroke
2. Stroke due to ischemia
3. Age 18 years or older
4. Ability to consent by patient (not surrogate), any time prior to acute hospital discharge

Exclusion Criteria:

1. Pre-stroke dependence (modified Rankin Scale score of 3 or more)
2. Isolated brainstem or cerebellar stroke
3. Bilateral acute strokes
4. Co-enrollment in a trial of an intervention through six-month follow-up
5. Inability to maintain follow-up with study procedures through six-month follow-up
6. Contraindication to non-contrast MRI
7. Low likelihood of survival beyond the acute hospitalization, such as malignant cerebral edema
8. Pre-existing co-morbid conditions that significantly affects vision, somatosensory function, vestibular system, orthostasis, coordination or mobility
9. Post stroke mRS\>4 or discharge to hospice

About the study

The primary objective of this proof-of-concept study is to longitudinally track the development of post-stroke sensory reweighting (PSR), identify associated structural neuroanatomical correlates, and investigate their relationship to walking and fall outcomes.

What is being tested

• Posturography (diagnostic test)
• Walking Speed (diagnostic test)
• Instrumented 7M Timed UP and GO (diagnostic test)
• Fall Event Records (other)
• MRI (3T) (diagnostic test)

Sponsor: University of Cincinnati · Participants: 45 · Started: Nov 1, 2024

Contact the study team

• oluwole Awosika, MD, MSCR · Phone: +1 513 558 2919
• Colin Drury, MS · Phone: 513 558 7656

Official record on ClinicalTrials.gov — NCT06727097

Locations in the U.S.

Conditions

• Ischemic Stroke

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.