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Ischemic Stroke clinical trials recruiting in the U.S.

93 studies for Ischemic Stroke are recruiting participants at sites across the United States.

A stroke is a medical emergency that should be treated immediately. Read about the causes, symptoms and treatments for an ischemic stroke.

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Recently updated studies

Assess the Safety and Efficacy of Sovateltide in Patients With Acute Cerebral Ischemic Stroke

RecruitingPhase 3
Ages 18 to 80 · All sexes · Updated Nov 13, 2026 · NCT05691244

FORWARD: Functional Outcomes in Real-World Treatment And Revascularization of Non-dominant and Distal M2 Occlusions

RecruitingObservational study
Ages 18 and older · All sexes · Updated Nov 12, 2026 · NCT07749170

Continuous Dual Aspiration Technique With Zoom System for Stroke

RecruitingObservational study
Ages 18 and older · All sexes · Updated Nov 6, 2026 · NCT07491952

Biomarkers of Paired VNS

Recruiting
Ages 18 to 80 · All sexes · Updated Nov 6, 2026 · NCT07922200

Hand and Arm Motor Recovery Via Non-invasive Electrical Spinal Cord Stimulation After Stroke

Recruiting
Ages 21 to 80 · All sexes · Updated Nov 4, 2026 · NCT05591196

Vagus Nerve Stimulation on Improving Sleep in Inpatient Rehab for Post-Acute Stroke

Recruiting
Ages 18 and older · All sexes · Updated Nov 4, 2026 · NCT07858656

The Rhythm Evaluation for AntiCoagulaTion With Continuous Monitoring of Atrial Fibrillation

RecruitingPhase 3
Ages 22 to 85 · All sexes · Updated Nov 3, 2026 · NCT05836987

Connectomic Alterations Following Acute Ischemic Stroke in the MCA Territory

Recruiting
Ages 18 and older · All sexes · Updated Oct 30, 2026 · NCT07584681

Neuromodulation-Enhanced Use of RObotic BALANCE Training to Improve Balance Function in Individuals With Stroke

Recruiting
Ages 18 to 75 · All sexes · Updated Oct 21, 2026 · NCT07113041

Thrombectomy Using Pulsed Aspiration for Reperfusion of Brain Occlusions

Recruiting
Ages 18 to 85 · All sexes · Updated Oct 21, 2026 · NCT06029491

Strategy for Improving Stroke Treatment Response

RecruitingPhase 2
Ages 18 and older · All sexes · Updated Oct 19, 2026 · NCT05948566

Study of BB-031 in Acute Ischemic Stroke Patients (RAISE)

RecruitingPhase 2
Ages 18 and older · All sexes · Updated Oct 13, 2026 · NCT06226805

Cognitive Strategies for Optimizing Brain Health And Managing Transgenerational Vascular Risk Factors Post-Stroke

RecruitingHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Oct 9, 2026 · NCT06479174

Vivistim Registry for Paired VNS Therapy (GRASP)

RecruitingObservational study
Ages 22 and older · All sexes · Updated Oct 9, 2026 · NCT05301140

Proximal Internal Carotid Artery Acute Stroke Secondary to Tandem or Local Occlusion Thrombectomy Trial

RecruitingPhase 3
Ages 18 to 79 · All sexes · Updated Oct 2, 2026 · NCT05611242

Intra-Arterial Magnesium Therapy After Mechanical Thrombectomy in Acute Ischemic Stroke

RecruitingPhase 1
Ages 21 to 95 · All sexes · Updated Oct 1, 2026 · NCT06956521

Non-Invasive Monitoring Methods in Patients With Acute Brain Injury

RecruitingObservational study
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT06504238

Brain Stimulation Effects on Post-Stroke Fatigue and Aphasia

Recruiting
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT07151677

kTMP-Enhanced Motor Rehabilitation for Chronic Stroke Recovery (KULMINATE) Pilot

Recruiting
Ages 18 to 80 · All sexes · Updated Sep 29, 2026 · NCT07631078

Blood Pressure Variability and Ischemic Stroke Outcome

RecruitingObservational study
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT05756257

Comparing the Safety and Efficacy of Apixaban and Rivaroxaban

RecruitingPhase 4
Ages 22 and older · All sexes · Updated Sep 23, 2026 · NCT06953726

Optimizing Reperfusion to Improve Outcomes and Neurologic Function

RecruitingPhase 2/3
Ages 18 to 90 · All sexes · Updated Sep 21, 2026 · NCT06990867

From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.