Home › Opioid Overdose › NCT06732596
Sustaining Recovery for People on Opioid Agonist Treatment With Conversational Agents
Who can join
Ages 18 and older · All sexes
Full eligibility criteria
Inclusion Criteria: * Diagnosis of Opioid Use Disorder (OUD) * Within 30 days of intake at recruitment site (BMC OBAT) * Possession of a smartphone that has minimum requirements * English-speaking and reading * Willing to release electronic health record (EHR) data * Able to provide at least two alternate contacts who usually know how to get in touch with them * Currently prescribed buprenorphine from an outpatient clinic Exclusion Criteria: * Incarceration anticipated within 12 months of enrollment * Inability to comprehend the study protocol, defined as failing three times to answer correctly a set of questions during the consent process * Inability to use the ECA app (i.e., due to markedly limited visual or auditory acuity or motor function required to interact with the ECA)
About the study
This study aims to improve retention in buprenorphine treatment, a medication used for opioid use disorder, through the use of a smartphone-delivered recovery support intervention. The intervention involves an Embodied Conversational Agent (ECA), a virtual, animated computer agent designed to simulate natural face-to-face conversations. ECAs have been shown to help individuals manage their healthcare in other settings, and this study seeks to evaluate their potential in supporting patients on medication for opioid use disorder (MOUD).
What is being tested
- Embodied conversational agent (ECA) (other)
- Technical support (other)
- Additional ECA messages (other)
- Additional incentives (other)
Sponsor: Boston Medical Center · Participants: 100 · Started: Oct 30, 2025
Contact the study team
- Karsten Lunze, MD MPH DrPH · Phone: 617 414 6933
- Samantha Blakemore, MPH · Phone: 617-383-9226
Official record on ClinicalTrials.gov — NCT06732596
Locations in the U.S.
| Massachusetts | Office-Based Addiction Treatment (OBAT) Clinic, BMC, Boston |
Conditions
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.