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Knee Injections for Obese Patients With Knee Arthritis

Comparison of Varying Doses of Steroid for Intra-articular Knee Injections

Who can join

Ages 55 to 85 · All sexes

Inclusion Criteria:

• Patients with BMI ≥30 kg/m2 and radiograph-proven knee osteoarthritis who are interested in receiving a steroid injection for knee arthritis.

Exclusion Criteria:

* BMI \< 30 kg/m2
* Uncontrolled diabetics with a hemoglobin A1c \> 8%
* No other treatment within the time frame of the study.
* Patients that are undergoing physical therapy at the time of the study.

About the study

The purpose of this study is to assess obese patients with knee arthritis and determine the non-inferiority of a low dose steroid treatment vs. standard dose steroid treatment for two knee outcome measures: pain and function.

What is being tested

• Triamcinolone Acetonide Low Dose (drug)
• Triamcinolone Acetonide Standard Dose (drug)

Sponsor: Mayo Clinic · Participants: 40 · Started: Jan 24, 2025

Contact the study team

• Jeffrey P Nadwodny, DO · Phone: 904 953 6722

Official record on ClinicalTrials.gov — NCT06782529

Locations in the U.S.

Conditions

• Knee Osteoarthritis
• Obesity

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.