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Tailored Anti-Inflammatory (A-I) Diet for Americans With Ulcerative Colitis (UC)
Recruiting
A Culturally Tailored Anti-inflammatory Diet for American Patients With Ulcerative Colitis
Who can join
Ages 16 to 75 · All sexes
Full eligibility criteria
Inclusion Criteria: * Documented diagnosis with ulcerative colitis from medical records. * Self-Identify as American * Ages 16-75 * SCCAI between 3-9 (no greater than 12 bowel movements a day) * Fecal calprotectin \> 150mg/dl. * On stable medications for their disease for the past 3 months * Likeability of American foods (sandwiches, BBQ or grilled meats and vegetables, baked potatoes, smoothies, salmon, oatmeal, avocado, soups) * No recent Inflammatory Bowel Disease (IBD) related hospitalization in the last month. Exclusion Criteria: * Diagnosis of Crohn's Disease (CD). * Prior ileoanal anastomosis (J-pouch) or diversion * No recent hospitalizations on the last 4 weeks * No Clostridium difficile or enteric infections on the last 4 weeks * No use of probiotics on the last 4 weeks * Patients following the specific carbohydrate diet or mediterranean diet or anti-inflammatory diet * No active cancer or conditions limiting their ability to follow a diet (heart failure, end stage renal disease) * Pregnancy, breastfeeding or planning to become pregnant during study period * Use of Total Parenteral Nutrition at the time of screening and during the study period * Other significant or life-threatening co-morbidities * The need for antibiotic use during the study period * Adults unable to consent * Ages less than 16 and \> 75 years old * Prisoners
About the study
The purpose of this study is to test the effect of an anti-inflammatory diet that incorporates native foods of the American diet on disease remission in American patients with Ulcerative Colitis (UC) and to identify biomarkers of response to dietary therapy.
What is being tested
- Catered diet (behavioral)
- Diet guidance sessions (behavioral)
- Dietary counseling (behavioral)
- Feedback sessions (behavioral)
Sponsor: University of Miami · Participants: 122 · Started: Mar 5, 2025
Contact the study team
- Oriana Damas, MD, MSCTI · Phone: 305 243-6405
- Eytan I Stern, MS, RD, LD/N, CNSC · Phone: 305 243-6405
Official record on ClinicalTrials.gov — NCT06784323
Locations in the U.S.
| Florida | University of Miami Health System, Miami |
Conditions
From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.